The patient had an uneventful recovery. Manipulation of the auger should be performed in a linear motion as best as possible and under fluoroscopic guidance.
The nonobese diabetic (NOD) mouse develops a high incidence of autoimmune diabetes and is believed to be a good model for insulin-dependent diabetes mellitus (IDDM) in humans. We isolated T-lymphocyte lines from islets of newly diabetic NOD mice, some of which are autoreactive to NOD spleen cells. Because autoreactive T-lymphocytes have been implicated in immune suppression, we injected NOD mice with an autoreactive T-lymphocyte line. The injected mice had a marked decrease in incidence of IDDM compared with control mice. Moreover, their islets showed no insulitis at 1 yr of age. We conclude that autoreactive T-lymphocytes can prevent the development of IDDM in NOD mice. This result suggests that 1) islets contain both effector cells capable of damaging pancreatic p-cells and cells able to regulate this autoimmune response, and 2) development of IDDM depends on the balance between these opposing forces. Diabetes 38:1647-51, 1989
Complex regional pain syndrome (CRPS) is characterized by pain that is out of proportion to the injury and is regional in distribution (1). It is primarily caused by peripheral trauma although approximately 10% occurs from lesions in central pain pathways. A large body of literature now exists both from animal models and clinical experience (2-7) supporting a dynamic change in the physiology and structure of central pain projecting
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