Poly(lactide-co-glycotide) (PLGA)/gelatin composite microspheres were prepared by an emulsion solvent evaporation technique. RGDS peptides were further immobilized under the catalyzation of water soluble carbodiimide (EDAC). Confocal laser scanning microscopy and transmission electron microscopy revealed that the gelatin was entrapped in the PLGA/gelatin microspheres with a manner of separated domains. The contents of the entrapped gelatin and immobilized RGDS peptides were quantified as 0.9 mg/20 mg and approximately 2.1 microg/20 mg microspheres by hydroxyproline analysis and bicinchoninic acid protein assay, respectively. Moreover, difference in morphology of PLGA, PLGA/gelatin and RGDS modified PLGA/gelatin (PLGA/gelatin-RGDS) microspheres was observed by scanning electron microscopy. The PLGA/gelatin and PLGA/gelatin-RGDS microspheres lost their weight rapidly in PBS, but slowly in DMEM/fetal bovine serum. Rabbit auricular chondrocytes were seeded onto the microspheres in vitro to assess their biological performance and applicability as cell carriers. Results show that amongst the PLGA, PLGA/gelatin and PLGA/gelatin-RGDS microspheres, the latter ones have the best performance in terms of chondrocyte attachment, proliferation, viability and sulfated glycosaminoglycans secretion.

In the present study, SWCNH–COOH and SWCNH–TETA were fabricated using single-walled carbon nanohorns (SWCNHs) via carboxylation and grafting with triethylenetetramine (TETA) for uranium (VI) ion [U­(VI)] removal. The morpho-structural characterization of as-prepared adsorbing materials was performed by transmission electron microscopy, X-ray diffractometry, Raman spectroscopy, and X-ray photoelectron spectroscopy (XPS). Several parameters including the pH value of the aqueous solutions, contact time, temperature, and U­(VI) concentration were used to evaluate the sorption efficiency of SWCNH–COOH and SWCNH–TETA. The Langmuir isotherm model could well represent the as-obtained adsorption isotherms, and the kinetics was successfully modeled by pseudo-second-order kinetics in the adsorption process. The maximum adsorption capacity of SWCNH–TETA was calculated as 333.13 mg/g considering the Langmuir isotherm model. Thermodynamic studies showed that adsorption proved to be a spontaneous endothermic process. Moreover, SWCNH–TETA exhibited excellent recycling performance and selective adsorption of uranium. Furthermore, the possible mechanism was investigated by XPS and density functional theory calculations, indicating that the excellent adsorption was attributed to the cooperation capability between uranium ions and nitrogen atoms in SWCNH–TETA. This efficient approach can provide a strategy for developing high-performance adsorbents for U­(VI) removal from wastewater.

PLLA microspheres were aminolyzed in hexanediamine/propanol solution to introduce free amino groups on their surface, which were further transferred into aldehyde groups by a treatment of glutaraldehyde. Chitosan-graft-lactose was then covalently coupled via Schiff base formation. Morphological variation and chitosan-graft-lactose immobilization were characterized. In vitro culture of rabbit auricular chondrocytes demonstrated that the PLLA microcarriers could effectively support the cell attachment and particularly induce cell aggregation on their surface. The formed cell aggregates/microcarriers composite showed higher viability and extracellular matrix production. Thus, the PLLA microcarriers can be potentially used as an injectable delivery system for cartilage repair.

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A three-dimensionally interconnected molybdenum trioxide (MoO 3 )/polypyrrole (PPy)/reduced graphene oxide (rGO) composite was synthesized via an eco-friendly three-step method. The as-obtained electrode shows a high specific capacity of 412.3 F g –1 at a current density of 0.5 A g –1 and a good cycling stability (85.1% of the initial specific capacitance after 6000 cycles at 2 A g –1 is retained), and these excellent electrochemical performances can be attributed to the unique structure, remarkable electrical conductivity, and the synergetic effects between MoO 3 , PPy, and rGO. Furthermore, a symmetric supercapacitor based on a MoO 3 /PPy/rGO electrode was assembled to investigate the practical application performance of this material. The results demonstrate a high energy density of 19.8 W h kg –1 at a power density of 301 W kg –1 . These findings shine a light on the rational design of electrode materials with multicomponents for high-performance supercapacitors.