Background: Caregivers of patients with alcohol and opioid use disorder (OUD) have low quality of life (QoL) and suffer from family stigma. However, impact of family stigma on QoL has not been studied in this population. Materials and Methods: One hundred primary caregivers of male inpatients with severe alcohol use disorder (AUD) ( n = 47) and OUD ( n = 53) as per the Diagnostic and Statistical Manual of Mental Disorders, 5 th Edition were enrolled into the cross-sectional, descriptive study.Participants were assessed using sociodemographic and clinical proforma, World Health Organization QoL-BREF Hindi, and Hindi family stigma scale. Kolmogorov–Smirnov tests and Pearson’s correlation were used for statistical analysis. Results: Majority of caregivers were females (64%), homemakers (48%), and married (80%). More than 50% of caregivers resided in rural areas and nuclear families. 46%, 30%, and 24% of caregivers were parents, wives, and siblings and children. Males, caregivers between 31 and 45 years of age, and married caregivers had significantly higher QoL. Parents had significantly lower QoL. Caregivers of patients with AUD had significantly lower overall QoL than that of OUD. Wives faced higher discrimination and overall stigma. Overall QoL, satisfaction with physical health, and environment were significantly negatively correlated with discrimination. Total stigma was negatively correlated with satisfaction with environment. Conclusion: Stigma and discrimination have negative impact on QoL of caregivers. Stigma reduction and QoL enhancement should be integral part of psychosocial interventions for caregivers of patients with AUD and OUD.
Ascaris migration from the intestine into the peritoneal cavity is rarely seen and the usual presentation is the acute abdomen. Our case report is of a young male who got admitted after a roadside accident with polytrauma including blunt trauma abdomen. When the patient was taken up for exploratory laparotomy, a freely lying tubular structure was noticed in the pelvis and small intestinal perforation. On inspection, it turned out to be an Ascaris worm. This is a case report of a rare presentation of Ascaris lumbricoides with jejunal perforation following blunt trauma. This blunt trauma could have been the cause of an intestinal perforation resulting from a concealed presence of an impending Ascaris perforation.
Objectives: Spouses of patients with alcohol use disorder (AUD) and opioid use disorder (OUD) suffer from burden, stigma, and low quality of life (QoL). The present study assessed the impact of stigma and burden on QoL among wives of patients with AUD and OUD. Methods: 90 wives of in-patients with severe AUD (n=54) and OUD (n=36) as per DSM-5 were assessed using socio-demographic pro forma, WHO QoL Bref Hindi, Hindi family stigma scale and Family Burden Interview Schedule. Statistical Package for the Social Sciences Inc., Chicago, IL, version 25.0 for Windows was used for analysis. Appropriate statistical tests including Kolmogorov–Smirnov tests of normality, Mann–Whitney test, and Kruskal–Wallis test were used. To see the relationship between two variables Pearson Correlation coefficient was calculated. All statistical tests were two-sided and performed at a significance level of α=.05. Results: Majority of the wives were more than 30 years old, literate and belonged to rural areas. Higher financial burden reduced overall QoL (p=0.001**), satisfaction with physical health (0.006**), psychological health (p=0.032*), and environment (p=0.001**). There was a negative correlation of satisfaction with environment with disruption of family interaction (p=0.003**), burden on mental health (p=0.001**), overall burden (p=0.000**), and discrimination (p=0.032*). Conclusion: QoL of spouses of patients with AUD and OUD reduces significantly due to stigma and burden. Enhancing QoL of spouses should be a part of management of AUD and OUD.
Objectives: The objectives of the study were to evaluate the patterns of cervical smear cytology in relation to human papillomavirus (HPV) and to correlate with histopathological diagnosis in females of 30 years and above. Methods: The 2-year prospective study was done in the Department of Pathology in 100 patients who attended the Gynaecology OPD of Govt. Medical College, Patiala. The cervical brushings obtained were subjected to cytological examination by liquid-based cytology through SurePath method and for HPV evaluation by BD Onclarity HPV assay. The cytological findings were further correlated with histopathological examination. Results: Majority of the females were in the age group of 30−45 years (62%). There was high incidence of dysplasia and malignancy in those who were of parity 3, 4, and above. The most common presenting symptom was discharge per vaginum (DPV) seen in 28% of cases. Maximum cases on cytology were diagnosed as NILM (including inflammatory pathology, 49%) followed by LSIL as 14% and malignant as 13%. Overall HPV genome was detected in 54% of the samples, the cases diagnosed as dysplasia and malignancy showed 68.42% and 100% presence of HPV, respectively. This was found to be statistically significant (p<0.05). Conclusion: Pap smear along with HPV evaluation is an effective screening method for the detection of pre-invasive lesions and cancers of cervix that are potentially curable.
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