Intrapericardial teratoma is a germ-cell tumor that typically arises from the base of the heart and usually diagnosed in the fetal or neonatal period. Although benign, these tumors can be massive in size causing direct compression of the heart. Life-threatening complications such as fetal hydrops, cardiac failure, superior vena cava syndrome, and cardiac tamponade caused by these teratomas have been reported. Early surgical excision is curative. We present the images of a mature intrapericardial teratoma diagnosed in an asymptomatic neonate. The neonate was managed successfully by elective surgical excision.
F. religiosa bark has been extensively used in traditional medicinal systems, such as Ayurveda, for its health benefits. The aim of this study was to investigate the secondary metabolites (phenolics and flavonoids) of the hydroalcoholic stem-bark extract from F. religiosa because this plant has been proven to have a beneficial effect on health disorders. Therefore, a pilot study was conducted for the identification and quantification of polyphenolic compounds in F. religiosa bark using sophisticated chromatographical techniques such as UPLC-HRMS and RP-HPLC-PDA. Additionally, total flavonoids, total phenolics and the scavenging profile of the bark were studied using a UV spectrophotometer. A total of 23 compounds identified with UPLC-HRMS were mainly phenolic acids, polyphenolics, and flavonoids (flavanols and proanthocyanidins). Among the identified compounds, gallic acid, catechin, epicatechin, epigallocatechin gallate, and ellagic acid were simultaneously quantified (0.031–0.380%) using RP-HPLC-PDA. Thereafter, the study complied by evaluating the total flavonoids (109.15 ± 1.2 mg RuE/g and 33.78 ± 0.86 mg CaE/g), total phenolics (4.81 ± 1.01 mg GaE/g), and scavenging profiles (IC50 13.75 ± 0.12 µg/mL) of the F. religiosa bark. This is the first report on the chemical profiling of F. religiosa bark, which is a necessary step to evaluate its nutraceutical properties, paving the way for possible food application.
A rapid, simple and validated reversed-phase high-performance liquid chromatographic method has been developed for analysis of oxaprozin in pharmaceutical dosage forms. Oxaprozin was separated on an ODS analytical column with a 45:55 (v/v) mixture of acetonitrile and triethanolamine solution (5 mM, pH 3.5 ± 0.05, adjusted by addition of 85% phosphoric acid) as mobile phase at a flow rate of 2.0 mL min −1 . The effluent was monitored by UV detection at 254 nm. Calibration plots were linear in the range 160 to 240 μg mL −1 and the LOD and LOQ were 14.26 and 41.21 μg mL −1 , respectively. The high recovery and low relative standard deviation confirm the suitability of the method for routine QC determination of oxaprozin in tablets.
The investigation was carried out at Samajik Vigyan Kendra, Dr. B.R. Ambedkar University, Bordi, Sehore (M.P.)-INDIA during kharif 2018-19. To assess the impact of insecticidal spray on leaf curling caused due to sucking pest and phytotoxic effect of higher doses of insecticides in chilli.The bio-efficacy of three different insecticides, namely (i) Chlorfenapyr 240 SC - spray four time with different-different doses, (ii) Fipronil 5% SC and (iii) Imidacloprid 17.8 SL. One untreated plot was also used to investigate against leaf curl and phytotoxic effect on chilli. Among these insecticides, Chlorfenapyr 240SC doses 288 g.a.i/hac (gram active ingredient per hactare) has least leaf curl indications (9.68%). It’s most effective insecticides in chilli. The least impact of leaf curl recorded in treatment T4- (9.68%) followed by T3- chlorofenapyr (11.88%),T5- Fipronil 5% SC (14.46%), T6- Imidacloprid (16.68%), T2- chlorofenapyr (17.69%) and the most elevated twisting in T7- untreated control (56.29). Further, the phytotoxic effect of treatment T1 - chlorfenapyr and T2 - chlorfenapyr were connected contrasting and T3 - untreated control. In these tried portions no phytotoxic impact likes chlorosis, Epinasty, Necrosis, Scorching , wilting and hyponasty were seen at various interim of perceptions against Chilli crop. The chilli yield was also noted highest in highest dose of T4 (16.0 tonnes ha-1) followed by second highest dose of T3 (15.4 tonnes ha-1), however, it was recorded lowest in untreated control (8.0 tonnes ha-1). The C:B benefit ratio was noted higher in T5- fipronil 5% SC@ 10 g.a.i ha-1 (3.20) followed by T6- imidacloprid 17.8 SL @ 50 g.a.i ha-1 (2.99).
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