BACKGROUND Use of antibiotics in sore throat is now getting out of hand as it has become very common to prescribe antibiotics for every sore throat patient. This has now led to increased antibiotic resistance in India. We wanted to evaluate proper use of antibiotics in cases of sore throat. METHODS A prospective study was done in 261 patients who were clinically diagnosed as acute tonsillitis or acute pharyngitis. Study was undertaken in a set up where most of the patients are from rural areas. Patients were analysed using Centor criteria and ASO (anti-streptolysin O where O stands for oxygen labile) titre for confirmation of streptococcal infection, and for negative results throat culture was done and antibiotics were prescribed accordingly and data was analysed by using chi square test for qualitative data with the help of statistical software SPSS v.25, and MS Excel. A p value of <0.05 was considered as statistically significant. RESULTS Results showed that 26.05% patients needed antibiotics while the rest 74% did well without antibiotics. CONCLUSIONS Centor criteria can be used to determine as to which patients need antibiotics straight away and ASO titer can be a useful test for poor patients as it can help in determining who actually needs antibiotics thus eliminating the irrational use.
BACKGROUND Endoscopic dacryocystorhinostomy (DCR) has certain advantages over the conventional external DCR. Failures in endo DCR are mainly due to reclosure of stoma in the lateral nasal wall. Mitomycin-C is an alkylating, an antiproliferative agent which reduces fibroblast collagen synthesis by inhibiting DNA dependent RNA synthesis and suppresses cellular proliferation when topically applied to mucosal tissues inhibit excessive scar tissue and granulation tissue formation. We wanted to evaluate the role of Mitomycin-C in endoscopic endo nasal DCR as an adjunct. METHODS Our prospective study was performed with 104 patients in 35-75 years age group who presented with chronic dacryocystitis. The study sample was designed randomly into Group A and group B. Group A patients were treated with Mitomycin-C to the incision site and Group B patients were not administered Mitomycin-C. These patients had 6 months of follow up. RESULTS 50 patients out of 52 in Group A had successful surgical outcome. In Group B 48 patients out of 52 were clinically free after the dacryocystorhinostomy. The results obtained had no significant difference between the Group A and Group B. CONCLUSIONS Use of intraoperative mitomycin-C is easy and safe but, in our study, it does not show any significant benefit in surgical outcome of endo DCR in preventing reclosure of stoma site.
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