Oncology nursing work environments can be improved by focusing on modifiable factors such as leadership, staff development and staffing resources, leading to better job satisfaction and hopefully retention of nurses.

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Standardization of patient-reported outcome data collection is key to assessing the impact of cancer and treatment on the person for population comparison and monitoring the quality of clinical care. The PROMS-Cancer Core taxonomy of domains and outcome measures can be used to guide the development of a patient-reported outcome information system for cancer.

The uptake of thymidine by oligodendrocytes in the brains of adult mice was examined after the induction of cortical traumatic lesions in an attempt to determine whether mature oligodendrocytes actively attached to myelin sheaths were capable of proliferating. In view of the great difficulty in visualizing the connection between a given oligodendrocyte and a myelin sheath even in the normal adult animal, the neuropil was made edematous in the traumatized animals in order to separate out the components and to study the oligodendrocyte processes. Uptake of tritiated thymidine was found in oligodendrocytes, as well as in endothelial cells, astrocytes, and microglia. The percentage of labeled oligodendrocytes appeared low in relation to the total number of the oligodendrocytes. In addition, in a few labeled cells, cytoplasmic processes could be seen extending to and apparently forming the myelin sheath. The possibility that a differentiated cell still attached to myelin may at the same time be able to proliferate is of great significance in understanding the potential for remyelination and recovery, in the adult, because it would imply that any oligodendrocyte is a candidate for proliferation, rather than only uncommitted or immature glial cells, which may be limited in the mature brain.

Providing quality clinical experiences for nursing students is vital to the development of safe and competent professional nurses. However, clinical educators often have difficulty identifying and coping with students whose performance is unsatisfactory. The purposes of this integrative review were to examine the extent and quality of the literature focusing on unsafe nursing students in clinical settings and to describe the characteristics of nursing students considered unsafe in clinical settings. A structured literature search yielded 11 relevant articles: five theoretical articles and six research studies. Analysis of findings revealed three themes: ineffective interpersonal interactions, knowledge and skill incompetence, and unprofessional image. The themes reflected the attitudes, actions, and behaviors that influenced students' ability to develop a safe milieu for client care. The findings provide clarity for early identification of students in need of increased support and facilitate clinical educators in meeting students' learning needs to ensure patient safety.