Although preschool-age children are at risk for witnessing domestic violence, the majority of research has focused on children ages 6 to 12 years. This study examines the mediating role of the mother-child relationship on preschool-age children's functioning in families experiencing domestic violence. Maternal report and behavioral observations of mother-child interactions were used to assess relationship quality. Participants consisted of 103 children and their mothers. The data fit the model well but indicated that some of the correlations were not in the expected direction. Although depressed mothers were struggling with parenting, other mothers appeared to be compensating for the violence by becoming more effective parents. Domestic violence negatively impacted children's behavior with their mothers in interactions but did not influence maternal report of problem behaviors, suggesting that the impact of domestic violence begins very early and in the realm of relationships rather than in mental health.
The posttraumatic stress symptoms of 39 children who had witnessed domestic violence and 23 children who were living in families with domestic violence were assessed by maternal report. Two measures of PTSD were used and compared, one based on the DSM-IV symptom list and one from the CBCL. Although all children had experienced at least one symptom of trauma, only 3% or 24% of the children, depending on the measure used, met criteria for PTSD based on the DSM-IV. Children with reexperiencing trauma symptoms also had more externalizing behavior problems. The applicability of DSM-IV criteria for young children and the use of the CBCL to assess trauma symptoms were questioned.
This study measured the prevalence of violence that customers, managers, pimps, and intimate partners perpetrated against 222 women in indoor and outdoor prostitution venues in Chicago, Illinois. Violence occurred in all of the prostitution activities but differed in frequency and severity. Women outdoors generally reported higher levels of physical violence, but women in indoor venues were frequently victims of sexual violence and being threatened with weapons. These findings indicate that women across prostitution venues are often victims of violence, arguing against the depiction of indoor sex trade activities as harmless, consensual entertainment.
Objective: The purpose of this study is to compare the incidence of congenital defects, spontaneous abortions, number of live births, fetal death and pre-maturity in women with autoimmune diseases taking HCQ during pregnancy.
Methods:The authors searched MEDLINE, Cochrane data base, Ovid-Currents Clinical Medicine, Ovid-Embase:Drugs and Pharmacology, EBSCO, Web of Science, and SCOPUS using the search terms HCQ and/or pregnancy. We attempted to identify all clinical trials from 1980 to 2007 regardless of language or publication status. We also searched Cochrane Central Library and http:/ /www.Clinical trials.gov for clinical trials of HCQ and pregnancy. Data were extracted onto standardized forms and were confirmed.
Results:The odds ratio (OR) of congenital defects in live births of women taking HCQ during pregnancy was 0.66, 95% confidence intervals (CI) 0.25, 1.75. The OR of a live birth for women taking HCQ during pregnancy was 1.05 (95% CI 0.58, 1.93). The OR of spontaneous abortion in women taking HCQ during pregnancy was 0.92 (95% CI 0.49, 1.72). The OR of fetal deaths in women taking HCQ during pregnancy was 0.97 (95% CI 0.14, 6.54). The OR of pre-mature birth defined as birth before 37 weeks in women taking HCQ during pregnancy was 1.10 (95% CI 0.75, 1.61).
Conclusion:HCQ is not associated with any increased risk of congenital defects, spontaneous abortions, fetal death, pre-maturity and decreased numbers of live births in patients with autoimmune diseases.
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