The aim of the present study was the morphometric evaluation of the epithelial lining and fibrous capsule in histological specimens of keratocystic odontogenic tumors (KOTs) before and after marsupialization. Histological sections from six KOTs that had undergone marsupialization followed by enucleation were photographed. The thickness and features of the capsule and of the epithelial lining of the tumor were evaluated upon marsupialization and upon subsequent enucleation using Axion Vision software. The histological specimens taken upon marsupialization presented an epithelial lining that is typical of KOTs. After marsupialization, the enucleated specimens had a modified epithelial lining and a fibrous capsule that both presented a greater median thickness (p = 0.0277 and p = 0.0212, respectively), morphological changes, and significant enlargement. These modifications can facilitate full surgical treatment and may well be related to a low KOT recurrence rate.
Spindle cell lipoma is an histological type of lipoma which are rarely found in the oral cavity. We describe two cases of intraoral spindle cell lipomas. The pa- tients were men and presented painless slow growing masses in the left cheek and hard palate, measuring 50 × 30 mm and 23 × 20 mm respectively. Microsco- pically, both lesions presented a solid proliferation of mature fat cells intermixed with bundles of connec- tive tissue. Cells were immunopositive for S100 pro- tein and CD34 (one case), with low mitotic activity (Ki-67). The final diagnosis was spindle cell lipomas. The lesions were excised and no recurrence was no- ticed after six months. Oral spindle cell lipomas are unexpected to occur in the oral mucosa, and the main differential diagnosis is well-differentiated liposar- coma/atypical lipoma. Lesions are treated with sur-gical excision and recurrences are rare
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