Beliefs about appearance-related changes due to aging were used to test the effects of perceived control and secondary control (acceptance) in a sample of 412 young, early-middle-age, and late-middle-age college-educated adults. Mean difference in aging-related appearance control and hypotheses regarding the adaptiveness of primary and secondary control were examined. Primary control over aging-related appearance was lower in older adults and secondary control was higher. In addition, the results indicated support for the Primacy/Back-Up Model that primary perceived control is important at all levels of actual control. Those with stronger beliefs in their primary control were less distressed. Secondary control served a back-up function in that it was related to less distress only for those who had medium or lower beliefs in primary control. The implications of these findings, that primary control may be advantageous even in low-control circumstances, are discussed.

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This paper summarizes the proceedings of a workshop held at Trinity Hall, Cambridge to discuss comparability and includes additional information and references to related information added subsequently to the workshop. Comparability is the need to demonstrate equivalence of product after a process change; a recent publication states that this ‘may be difficult for cell-based medicinal products’. Therefore a well-managed change process is required which needs access to good science and regulatory advice and developers are encouraged to seek help early. The workshop shared current thinking and best practice and allowed the definition of key research questions. The intent of this report is to summarize the key issues and the consensus reached on each of these by the expert delegates.

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Abstract-We are in an age where people are paying increasing attention to energy conservation around the world. The heating and air-conditioning systems of buildings introduce one of the largest chunk of energy expenses. In this paper, we make a key observation that after a meeting or a class ends in a room, the indoor temperature will not immediately increase to the outdoor temperature. We call this phenomenon Thermal Inertia. Thus, if we arrange subsequent meetings in the same room; than a room that has not been used for some time, we can take advantage of such un-dissipated cool or heated air and conserve energy.We develop a green room management system with three main components. First, it has a wireless sensor network to collect indoor, outdoor temperature and electricity expenses of the air-conditioning devices. Second, we build an energy temperature correlation model for the energy expenses and the corresponding room temperature. Third, we develop room scheduling algorithms. Our system is validated with real deploy ment of a sensor network for data collection and thermodynamics model calibration. We conduct a comprehensive evaluation with synthetic room and meeting configurations. We observe a 30% energy saving as compared with the current schedules.

Human pluripotent stem cells (hPSCs) have the potential to transform medicine. However, hurdles remain to ensure safety for such cellular products. Science-based understanding of the requirements for source materials is required as are appropriate materials. Leaders in hPSC biology, clinical translation, bio-manufacturing and regulatory issues were brought together to define requirements for source materials for the production of hPSCderived therapies and to identify other key issues for the safety of cell therapy products. Whilst the focus of this meeting was on hPSC-derived cell therapies, many if the issues are generic to all cell-based medicines. The intent of this report is to summarise the key issues discussed and record the consensus reached on each of these by the expert delegates.