Introduction: Pulmonary insufficiency (PI) frequently develops in patients who underwent repair of tetralogy of fallot (TOF). The aim of present study was to assess the effect of pulmonary valve replacement (PVR) on hemodynamics of patients who underwent repair of TOF.
Methods: This retrospective cohort carried out between July 2010 and October 2012 among consecutive PVRs of 19 patients who underwent TOF surgery. The PVRs was performed using bioprosthetic (n=17) and mechanical (n=2) valves. Our data was collected during follow up visits within 6 to 12 month after PVR.
Results: Our results show that PVR significantly decreased right ventricular end-diastolic volume (180.89±13.78 vs. 107.21±12.02 ml/m2, P < .01), right ventricular end-systolic volume (105.42±15.98 vs. 58.15±11.67 ml/m2, P < .01), RV mass (47.78±6.20 vs. 30.68±8.95 g/m2, P < .01), and PI (48.21±1.43% vs. 12.68±5.60%, P < .01). Moreover, left ventricular end-diastolic volume significantly increased (78.05±17.21 vs. 90.78±14.82 ml/m2, P < .01) after PVR. The other hemodynamics indexes did not change, significantly.
Conclusion: Despite the controversies about efficacy of PVR after repair of TOF, the remarkable improvement of hemodynamic is a supportive rationale for performing PVR surgery in TOF patients.
Background and aims:Much of early medical and nursing practice was based on nonscientific traditions that resulted in variable and haphazard patient outcomes. These traditions and rituals, which were based on folklore, gut instinct, trial and error, and personal preference, were often passed down from one generation of practitioner to another. It has become essential for practitioners to use the best data available to make patient care decisions and carry out the scientific and evidence-based interventions. The aim of this study is suggestion of a framework for easily translation of evidence-based knowledge into clinical practice.Methods:This discussion paper explains the process that evidence-based knowledge is created from crude scientific knowledge, disseminated among stakeholders, implemented into clinical practice and ultimately evaluated. In May 2014, the primary author searched electronic and scientific databases without limiting searches by publication date, to find applicable literature.Results:This framework presented how evidence-based knowledge can be created and distributed among stakeholders to implement into practice. Additionally, this framework explains interactions between stakeholders, context, and evidence-based knowledge from acquirement to adherence. Knowledge can easily translate into clinical practice by step-by-step following of 4 phases consisted of knowledge creation, knowledge dissemination, knowledge implementation, evaluation and feedback.Conclusion:Today, evidence based knowledge translation has become an imperative component for healthcare disciplines and identified as one of most important priorities of present millennium. Evidence-based knowledge translation is a simple and feasible way to bridging the gap between evidence-based knowledge and clinical practice that can be carry out trough utilization of current conceptual framework.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.