Radiographic patterns on CT chest scans have shown higher sensitivity and specificity compared to RT-PCR detection of COVID-19 which, according to the WHO has a relatively low positive detection rate in the early stages. We technically review a study that compared multiple convolutional neural network (CNN) models to classify CT samples with COVID-19, Influenza viral pneumonia, or no-infection. We compare this mentioned study with one that is developed on existing 2D and 3D deeplearning models, combining them with the latest clinical understanding, and achieved an AUC of 0.996 (95%CI: 0.989-1.00) for Coronavirus vs Non-coronavirus cases per thoracic CT studies. They calculated a sensitivity of 98.2% and a specificity of 92.2%.
Attachment security is hypothesized to promote authenticity and sincerity, or honesty, whereas insecurity is hypothesized to increase various forms of inauthenticity and dishonesty. The authors tested these ideas in 8 studies of dispositional and situational attachment insecurities and their influence on inauthenticity and dishonesty. The first 4 studies showed that authenticity is related to scoring low on the 2 dimensions of dispositional attachment insecurity-anxiety and avoidance-and that these 2 dimensions are associated with different aspects of inauthenticity. The first set of studies also showed that conscious and unconscious security priming increased state authenticity (compared with neutral or insecurity priming). The last 4 studies showed that attachment insecurity is related to dishonesty (lying and cheating) and that security priming reduces the tendency to lie or cheat and does so more effectively than positive mood priming. Implications for understanding the role of authenticity and inauthenticity in various relationship contexts are discussed.
Attachment theory attempts to explain effects of social experiences, not genes, on personality development. Most studies of the development of attachment insecurities support this emphasis on social experiences rather than genes, although there are exceptions. In the present study, the authors examine associations between attachment insecurities and particular genetic polymorphisms related to emotions and social behavior. They find that (a) anxious attachment is associated with a polymorphism of the DRD2 dopamine receptor gene, (b) avoidant attachment is associated with a polymorphism of the 5HT2A serotonin receptor gene, and (c) the rs53576 A polymorphism of the OXTR oxytocin receptor gene is not associated with attachment insecurities. These findings suggest that attachment insecurities are partially explained by particular genes, although there is still a great deal of individual difference variance that remains to be explained by other genes or social experiences.
This study was designed to evaluate the incidence and risk factors associated with the occurrence of junctional ectopic tachycardia (JET) in patients after congenital heart surgery. We prospectively analyzed cardiac rhythm status in 336 consecutive patients undergoing surgery for congenital heart disease at our institution during a 1-year period. The incidence of JET was 8% (27/336). Repairs with the highest incidence of JET were arterial switch operation (3/13, 23%), atrioventricular (AV) canal repair (4/19, 21%), and Norwood repair (2/10, 20%). Compared to patients with no arrhythmias, patients with JET were more likely to be younger (2.75 +/- 2.44 vs 5.38 +/- 7.25 years, p < 0.01), have had longer cardiopulmonary bypass times (126 +/- 50 vs 85 +/- 73, p < 0.01), and have a higher inotrope score (6.26 +/- 7.55 vs 2.41 +/- 8.11, p < 0.01). By multivariate analysis, ischemic time was the only factor associated with JET [odds ratio, 1.01 (confidence interval, 1.005-1.02); p = 0.0014). The presence of JET did not correlate with electrolyte abnormalities. JET is not necessarily related to surgery near the His bundle or hypomagnesemia. Longer ischemic time is the best predictor of JET. Patients undergoing arterial switch operation, AV canal repair, and Norwood repair are at highest risk of postoperative JET and should be considered for prophylactic therapy.
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