Milk whey is effective in enhancing the production of satiety hormones as GLP-1 and CCK depending on the phase of digestion and origin of milk whey.
Plant extract activity can be modified by the digestion process. In order to assess the satiety effect of green tea and turmeric extracts, an in vitro gastrointestinal digestion process was performed and the STC-1 cell line was used. The enteroendocrine cell line was incubated (for 30, 60 and 120 minutes) with the digested and non-digested extracts measuring the secretion of cholecystokinin (CCK) and glucagon-like peptide-1 (GLP-1) by enzyme-linked immunosorbent assay (ELISA). The release of satiety hormones by the STC-1 cells showed similar or higher results for plant extracts compared to the positive controls reported as satiatogenic (proteins and short chain fatty acids). For the non-digested samples, the largest amount of CCK and GLP-1 was found for turmeric, with 379 ± 46 pg ml-1 (60 min) and 347 ± 125 pg ml-1 (120 min) respectively. For the digested samples, the highest level of CCK was found for turmeric at 30 minutes (43.3 ± 11) and for GLP-1 by green tea at 120 minutes (165.7 ± 52). The in vitro gastrointestinal digestion process affects the satiety of plant extracts, increasing for green tea and decreasing for turmeric. Green tea showed the most stable satiating capacity after the in vitro digestion process and this may be useful for using it as a stable food supplement to reduce hunger associated with overweight and obesity.
Nowadays, overweight and obesity has reached an epidemic level around the world. With the aim to tackle them, an interesting strategy is the study of food and ingredients with satiety properties. In addition to reducing food and/or calorie intake, this type of foods must be included as part of a healthy diet. With regard to this, it is well known that the Mediterranean Diet (MD) is a feeding pattern that helps us to maintain good health, providing an adequate intake of micronutrients and active compounds. With this background, the main aim of this research was to identify MD foods with a high satiating potential capacity. For this purpose, three typical foods of the Mediterranean region, mainly based on vegetables, were selected: hummus, ajoblanco and gazpacho. As a control, white bread was used. Twenty-four human healthy volunteers consumed a standard breakfast followed by the different typical Mediterranean foods, and then the subjective sensation of hunger and satiety for each food was assessed by visual analogue scales (VAS) during 3 h. Subsequently, volunteers had ad libitum access to a standard meal. The results indicate that gazpacho showed the highest satiating scores, despite the fact that it was not the food that provided the highest protein or fibre amount. More studies of this type are needed to determine the proportion and/or combination of ingredients from these classical Mediterranean recipes that could enhance human satiety.
Debido al gran aumento de la prevalencia del sobrepeso y obesidad en todo el mundo, ha aumentado el inte- rés de estudio de los mecanismos que llevan a la población a un desequilibrio energético, aumentando su peso corporal de forma excesiva. El control de la ingesta de energía va determinado por la percepción de la saciedad durante y después de las comidas. Hay ciertos alimentos que por sus características nutricionales (cantidad de fibra, hidratos de carbono, proteína y grasa) pueden influenciar de forma positiva sobre el apetito (disminuyen- do el deseo por la comida). Por ello sería una buena estrategia nutricional ver cuáles de los alimentos presenta mayor relación sobre la saciedad. Realizamos un ensayo clínico cruzado aleatorizado con un periodo de lavado de 5 días, como mínimo. El objetivo del presente estudio fue evaluar el efecto de las semillas de sésamo y chía (por su gran cantidad de fibra soluble) sobre la saciedad (introducidas junto con yogur en el desayuno). La muestra estaba formada por 18 voluntarios. Cada voluntario realizó los 3 tipos de desayunos de forma aleatoria: (café con leche o té con leche + tostada con aceite de oliva y sal) + (yogur, yogur con chía o yogur con sésamo). Antes del desayuno tuvieron que rellenar una encuesta sobre apetito (VAS) y después 7 más (a los 15, 45, 75, 105, 135, 165 y 195 minutos tras el desayuno). Para valorar el efecto saciante de las semillas, se analizaron las preguntas del VAS que presentan relación directa con la saciedad, y se realizó un ANOVA. Los resultados mos- traron que no había diferencias estadísticamente significativas (p>0.05) entre las semillas estudiadas. Nowadays, there is a high prevalence of overweight and obesity around the world, so the inter- est in studying the mechanisms that lead the population to an energy imbalance has increased. The control of energy intake is determined by the perception of satiety during and after meals. There are certain foods that, due to their nutritional characteristics (amount of fibre, carbohydrates, protein and fat), can positively influence the appetite (decreasing the desire to eat). Thus, it would be a good nutritional strategy to see which foods have a greater satiety effect. We performed a randomi- zed crossover clinical trial with at least 5-days washout period. The objective of the present study was to evaluate the effect of sesame and chia seeds (due to their large amount of soluble fibre) on satiety. The sample consisted of 18 volunteers. Each one performed the 3 types of breakfasts randomized: (coffee with milk or tea with milk + toast with olive oil and salt) + (yoghurt, yoghurt with chia or yoghurt with sesame). Before breakfast they had to fill out an appetite survey (VAS) and then 7 more (at 15, 45, 75, 105, 135, 165 and 195 min after breakfast). To assess the satiating effect of the seeds, the questions of the VAS directly related to satiety were analysed, and ANOVA was performed. The results showed that there were no statistically significant differences (p>0.05) between seeds.
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