News content can sometimes be misleading and influence users' decision making processes (e.g., voting decisions). Quantitatively assessing the truthfulness of content becomes key, but it is often challenging and thus done by experts. In this work we look at how experts and non-expert assess truthfulness of content by focusing on the effect of the adopted judgment scale and of assessors' own bias on the judgments they perform. Our results indicate a clear effect of the assessors' political background on their judgments where they tend to trust content which is aligned to their own belief, even if experts have marked it as false. Crowd assessors also seem to have a preference towards coarse-grained scales, as they tend to use a few extreme values rather than the full breadth of fine-grained scales.
Breast cancer is the most common malignancy in women worldwide, and is responsible for more than half a million deaths each year. The appropriate therapy depends on the evaluation of the expression of various biomarkers, such as the human epidermal growth factor receptor 2 (HER2) transmembrane protein, through specialized techniques, such as immunohistochemistry or in situ hybridization. In this work, we present the HER2 on hematoxylin and eosin (HEROHE) challenge, a parallel event of the 16th European Congress on Digital Pathology, which aimed to predict the HER2 status in breast cancer based only on hematoxylin–eosin-stained tissue samples, thus avoiding specialized techniques. The challenge consisted of a large, annotated, whole-slide images dataset (509), specifically collected for the challenge. Models for predicting HER2 status were presented by 21 teams worldwide. The best-performing models are presented by detailing the network architectures and key parameters. Methods are compared and approaches, core methodologies, and software choices contrasted. Different evaluation metrics are discussed, as well as the performance of the presented models for each of these metrics. Potential differences in ranking that would result from different choices of evaluation metrics highlight the need for careful consideration at the time of their selection, as the results show that some metrics may misrepresent the true potential of a model to solve the problem for which it was developed. The HEROHE dataset remains publicly available to promote advances in the field of computational pathology.
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