We rep ort a cas eofperineural invasion ofthefacial nerve by a cuta neous squamous cell carcinotna in a 59-year-oldman who p rese nted with a slowly p rogressive facial paralys is. We perfonned a distalfa cial nerve dissection and a simp le mastoidectomy witlifacial recess exposurefor rese ction to negati ve tnarg ins. Wealso peiformeda simultaneousfacial recon struction and reanitnatio n procedure with exc ellent results. External-beam radiation comp leted the treatment regimen. In addition to deser ihing this case, we review current co ncepts in diagnos is and therapy. as weil as the historieal backg round of malignant perineural invasion ofthe cranial nerv es.
Solitary fibrous tumors are relatively rare mesenchymal neoplasms that were originally described as pleural- or peritoneal-based lesions. Although they were considered a form of mesothelioma, subsequent investigation failed to reveal mesothelial differentiation. Characterization of their histologic and immunohistochemical features, as well as identification in a multitude of nonmesothelial-based locations has further served to distinguish these lesions from the more diffuse and aggressive mesothelioma. Reports of solitary fibrous tumor in the larynx are extremely rare. We report a case of solitary fibrous tumor of the larynx in a 38-year-old man.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.