Several possible mechanisms by which sex hormones may influence development of osteoarthritis in mice have been investigated. No relationship existed between the joint disease and mineral content of the bone. A sexual dimorphism in femur length is described for the first time. Strain differences in the effect of sex hormones on the joints of STR/lN and other strains of mice cannot be accounted for by a proposed "dyschondrogenesis."Esseva investigate plure possible mechanismos per que hormones sexual pote influentiar le disveloppamento de osteoarthritis in muses. Nulle relation esseva trovate le inter le morbo articular e le contento mineral del osso. Un dimorphismo sexual in le Iongor del femore es describite pro le prime vice. Differentias inter muses STR/lN e altere lineas con respecto a1 effect0 del hormones de sex0 super le articulationes non pote esser explicate per un proponite "dyschondrogenese."