The Unified Huntington's Disease Rating Scale (UHDRS) was developed as a clinical rating scale to assess four domains of clinical performance and capacity in HD: motor function, cognitive function, behavioral abnormalities, and functional capacity. We assessed the internal consistency and the intercorrelations for the four domains and examined changes in ratings over time. We also performed an interrater reliability study of the motor assessment. We found there was a high degree of internal consistency within each of the domains of the UHDRS and that there were significant intercorrelations between the domains of the UHDRS, with the exception of the total behavioral score. There was an excellent degree of interrater reliability for the motor scores. Our limited longitudinal database indicates that the UHDRS may be useful for tracking changes in the clinical features of HD over time. The UHDRS assesses relevant clinical features of HD and appears to be appropriate for repeated administration during clinical studies.
We compared three approaches to scoring qualitative aspects of verbal fluency performance in 88 healthy young adults. Phonemic and semantic fluency output was scored for word clustering and switching between clusters. Convergent validity analyses using other tests presumed to tap into strategy use (California Verbal Learning Test, Ruff Figural Fluency Test) support scoring of phonemic and semantic clusters on both fluency tasks. Task-discrepant clustering (e.g., semantic clustering on phonemic fluency) may index intentional strategy use on both fluency tasks, whereas task consistent clustering (e.g., phonemic clustering on phonemic fluency) appears strategic only on semantic fluency. Switching can be decomposed into subtypes that appear to reflect different cognitive processes on phonemic versus semantic fluency. Principal components analyses suggest that earlier scoring methods do not fully capture the "process" aspects of verbal fluency performance.
Institutionalized patients with HD are more motorically, psychiatrically, and behaviorally impaired than their counterparts living at home. However, motor variables alone predicted institutionalization. Treatment strategies that delay the progression of motor dysfunction in HD may postpone the need for institutionalization.
The authors examined the effects of interactions (a) between defendant attractiveness and juror gender and (b) between defendant race and juror race on judgment and sentencing among 207 Black, Hispanic, and White participants in the United States. After reading a vehicular-homicide vignette in which the defendant's attractiveness and race varied, the participants rated guilt and recommended sentences. The women treated the unattractive female defendant more harshly than they treated the attractive female defendant; the men showed an opposite tendency. The Black participants showed greater leniency when the defendant was described as Black rather than White. The Hispanic participants showed an opposite trend, and the White participants showed no race-based leniency. The findings on racial effects were consistent (a) with in-group favorability bias among the Black participants and (b) with attribution effects unrelated to race among the White participants.
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