Use of autism diagnosing standards in low‐income countries (LICs) are restricted due to the high price and unavailability of trained health professionals. Furthermore, these standards are heavily skewed towards developed countries and LICs are underrepresented. Due to such constraints, many LICs use their own ways of assessing autism. This is the first retrospective study to analyze such local practices in Sri Lanka. The study was conducted at Ward 19B of Lady Ridgeway Hospital (LRH) using the clinical forms filled for diagnosing ASD. In this study, 356 records were analyzed, from which 79.5% were boys and the median age was 33 months. For each child, the clinical form together with the Childhood Autism Rating Scale (CARS) value were recorded. In this study, a Clinically Derived Autism Score (CDAS) is obtained from the clinical forms. Scatter plot and Pearson product moment correlation coefficient were used to benchmark CDAS with CARS, and it was found CDAS to be positively and moderately correlated with CARS. In identifying the significant variables, a logistic regression model was built based on clinically observed data and it evidenced that “Eye Contact,” “Interaction with Others,” “Pointing,” “Flapping of Hands,” “Request for Needs,” “Rotate Wheels,” and “Line up Things” variables as the most significant variables in diagnosing autism. Based on these significant predictors, the classification tree was built. The pruned tree depicts a set of rules, which could be used in similar clinical environments to screen for autism.
Lay Summary
Screening and diagnosing autism in low‐income countries such as Sri Lanka has always been a challenge due to limited resources and not being able to afford global standards. Due to these challenges, locally developed clinical forms have been used. This study is the first to analyze a clinical record set for autism in Sri Lanka to benchmark the local clinic form with a global standard. Furthermore, this study identifies the most significant diagnostic symptoms for children and based on these significant features, a simple set of IF–THEN rules are derived which could be used for screening autism in a similar clinical environment by health officials in the absence of consultants.
most destructive diseases of potato. The use of healthy seed potatoes is the most effective means to control the disease. Ralstonia solanacearum, the causal organism of bacterial Therefore, there is a requirement to detect R. solanacearum in seed potatoes quickly and reliably for quarantine purposes. R. solanacearum in potato tubers for quarantine purposes. The based method for detection of R. solanacearum in potatoes 2 cfumL-1 sensitivity. The developed detection method is user-friendly as it does not require more complicated and method more appropriate for quarantine purposes in Sri Lanka.
Summarizing or averaging a sequential data set (i.e., a set of time series) can be comprehensively approached as a result of sophisticated computational tools. Averaging under Dynamic Time Warping (DTW) is one such tool that captures consensus patterns. DTW acts as a similarity measure between time series, and subsequently, an averaging method must be executed upon the behaviour of DTW. However, averaging under DTW somewhat neglects temporal aspect since it is on the search of similar appearances rather than stagnating on corresponding time-points. On the contrary, the mean series carrying point-wise averages provides only a weak consensus pattern as it may over-smooth important temporal variations. As a compromise, a pool of consensus series termed Ultimate Tamed Series (UTS) is studied here that adheres to temporal decomposition supported by the discrete Haar wavelet. We claim that UTS summarizes localized patterns, which would not be reachable via the series under DTW or the mean series. Neighbourhood of localization can be altered as a user can customize different levels of decomposition. In validation, comparisons are carried out with the series under DTW and the mean series via Euclidean distance and the distance resulted by DTW itself. Two sequential data sets are selected for this purpose from a standard repository.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.