Physical exercise can blunt some of the negative side effects of breast cancer treatment, including reduced physical functioning. Self-directed exercise is an effective way to improve physical functioning compared with usual care. In participants not receiving chemotherapy, supervised exercise may increase aerobic capacity and reduce body weight compared with usual care.

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The greater saphenous vein is vulnerable in its superficial course overlying the distal tibia in the zone of impact of a kicker's foot Minor repetitive trauma or a single traumatic event to this area may subject the vein to intimai trauma or other irregularities that may lead to vein thrombosis.

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