Background: Hepatitis C infection is a major health problem around the world. It exhibits high genetic diversity, characterized by regional variations in genotype distribution. It seems that the hepatitis C virus genotypes are differently distributed between distinct geographical regions and also associated with different clinical outcomes and response to antiviral therapy. Objectives: The current study was performed to identify the distribution of HCV genotypes among chronic patients, who were HCV positive in Rasht, Capital City of Guilan Province, and Northern Part of Iran.
Patients and Methods:The cross sectional study was carried out from June 2014 to February 2015. A total of 83 patients with anti-HCV-positive specimens were enrolled. Detection of HCV-RNA by Real Time-Polymerase Chain Reaction (RT-PCR) was performed from anti-HCV positive specimens, and HCV genotypes among plasma samples from RNA-HCV positive patients were then investigated using type-specific primers.
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