Wearable devices now make it possible to record large quantities of physiological data, which can be used to obtain a clearer view of a person’s health status and behavior. However, to the best of our knowledge, there are no open datasets in the literature that provide psycho-physiological data. The Multilevel Monitoring of Activity and Sleep in Healthy people (MMASH) dataset presented in this paper provides 24 h of continuous psycho-physiological data, that is, inter-beat intervals data, heart rate data, wrist accelerometry data, sleep quality index, physical activity (i.e., number of steps per second), psychological characteristics (e.g., anxiety status, stressful events, and emotion declaration), and sleep hormone levels for 22 participants. The MMASH dataset will enable the investigation of possible relationships between the physical and psychological characteristics of people in daily life. Data were validated through different analyses that showed their compatibility with the literature.

Studies with event-related potentials have highlighted deficits in the early phases of orienting to left visual targets in right-brain-damaged patients with left spatial neglect (N+). However, brain responses associated with preparatory orienting of attention, with target novelty and with the detection of a match/mismatch between expected and actual targets (contextual updating), have not been explored in N+. Here in a study in healthy humans and brain-damaged patients of both sexes we demonstrate that frontal activity that reflects supramodal mechanisms of attentional orienting (Anterior Directing Attention Negativity, ADAN) is entirely spared in N+. In contrast, posterior responses that mark the early phases of cued orienting (Early Directing Attention Negativity, EDAN) and the setting up of sensory facilitation over the visual cortex (Late Directing Attention Positivity, LDAP) are suppressed in N+. This uncoupling is associated with damage of parietal-frontal white matter. N+ also exhibit exaggerated novelty reaction to targets in the right side of space and reduced novelty reaction for those in the left side (P3a) together with impaired contextual updating (P3b) in the left space. Finally, we highlight a drop in the amplitude and latency of the P1 that over the left hemisphere signals the early blocking of sensory processing in the right space when targets occur in the left one: this identifies a new electrophysiological marker of the rightward attentional bias in N+. The heterogeneous effects and spatial biases produced by localized brain damage on the different phases of attentional processing indicate relevant functional independence among their underlying neural mechanisms and improve the understanding of the spatial neglect syndrome. Our investigation answers important questions: are the different components of preparatory orienting (EDAN, ADAN, LDAP) functionally independent in the healthy brain? Is preparatory orienting of attention spared in left spatial neglect? Does the sparing of preparatory orienting have an impact on deficits in reflexive orienting and in the assignment of behavioral relevance to the left space? We show that supramodal preparatory orienting in frontal areas is entirely spared in neglect patients though this does not counterbalance deficits in preparatory parietal-occipital activity, reflexive orienting, and contextual updating. This points at relevant functional dissociations among different components of attention and suggests that improving voluntary attention in N+ might be behaviorally ineffective unless associated with stimulations boosting the response of posterior parietal-occipital areas.

Our daily-life actions are typically driven by vision. When acting upon an object, we need to represent its visual features (e.g. shape, orientation, etc.) and to map them into our own peripersonal space. But what happens with people who have never had any visual experience? How can they map object features into their own peripersonal space? Do they do it differently from sighted agents? To tackle these questions, we carried out a series of behavioral experiments in sighted and congenitally blind subjects. We took advantage of a spatial alignment effect paradigm, which typically refers to a decrease of reaction times when subjects perform an action (e.g., a reach-to-grasp pantomime) congruent with that afforded by a presented object. To systematically examine peripersonal space mapping, we presented visual or auditory affording objects both within and outside subjects’ reach. The results showed that sighted and congenitally blind subjects did not differ in mapping objects into their own peripersonal space. Strikingly, this mapping occurred also when objects were presented outside subjects’ reach, but within the peripersonal space of another agent. This suggests that (the lack of) visual experience does not significantly affect the development of both one’s own and others’ peripersonal space representation.

Introduction The vaccination coverage decline and the re-emergence of vaccine preventable diseases draw attention to the problem of vaccine hesitancy (VH). Many studies demonstrated that the current vaccine education is not very effective. We analysed the problem of VH in relation to Health Literacy (HL) and the perception of vaccine preventable diseases-related risks in a sample of parents. Methods We conducted a survey among parents between February and November 2018. We collected data on demographic, main sources of information, vaccination attitude (using the Vaccine Confidence Index (VCI) adapted from Larson HJ 2016), HL levels(using an adapted version of IMETER and knowledge of signs and symptoms of diphtheria, tetanus and measles. Results The study included 772 parents, 620 women (mean age 39 years), 48.2% had diploma. The main source of information was the doctor (85.5%) followed by the web(24.2%). The average VCI was 3.78(range: 0.1-10) with lower values among parents informed through social networks (2.05-2.78). Analysing the IMETER test, 90% had a good or acceptable level of HL. No significant correlation between VCI and HL was found. For parents who identified at least 3 specific elements of selected diseases, the average VCI was significantly higher(Measles 4.32,Tetanus 4.64,Diphtheria 5.84). Conclusions The HL level did not correlate with the VCI. A low VCI was associated with poor knowledge of selected diseases: this confirms the importance of a correct risk perception. This study in accordance with the literature suggests to amplify the model used to analyse the VH taking into account cognitive biases (i.e. ambiguity aversion and omission bias) as important factor affecting the parents' decision making. We aim to expand our work building a survey to categorise parents according their main cognitive bias. This may be useful to understand the better communication strategies to effectively have an impact on each parents' behaviour. Key messages This study in accordance with the literature suggests to amplify the model used to analyse the VH taking into account cognitive biases. The Health Literacy is not enough to explain the problem of the Vaccine Hesitancy.

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Globalization phenomena and Information Communication Technology (ICT) are producing deep changes worldwide. The economic environment and society where firms both cooperate and compete with each other are rapidly changing leading firms towards recognizing the role of intangible resources as a source of fresh competitive advantage. Experience, innovation and the ability to create new knowledge completely arise from the act of human resources inviting firms to focus on how to generate and shape knowledge. Therefore, the future of firms depends greatly on how managers are able to explore and exploit human resources. However, without a clear understanding of the nature of human beings and the complexity behind human interactions, we cannot understand the theory of organizational knowledge creation. Thus, how can firms discover, manage and valorize this "human advantage"? Neuroscience can increase the understanding of how cognitive and emotional processes work; in doing so, we may be able to better understand how individuals involved in a business organization make decisions and how external factors influence their behavior, especially in terms of commitment activation and engagement level. In this respect, a neuroscientific approach to business can support managers in decision-making processes. In a scenario where economic humanism plays a central role in the process of fostering firms' competitiveness and emerging strategies, we believe that a neuroscience approach in a business organization could be a valid source of value and inspiration for manager decision-making processes.