The purpose of this paper was to study the possible causes of Non-Specific Reactive Hepatitis (NSRH) in tissue samples of housed dogs that were collected from different cities of Andalucia (Spain). Histologically, this disease was characterized by the presence of lymphocytes and plasma cells spread throughout the liver parenchyma and in the portal stroma, with no evidence of hepatocyte necrosis. These animals showed non-specific chronic reactive hepatitis that varied from moderate to severe. In order of prevalence, the more common pathologies associated with NSRH were gastrointestinal and renal diseases, as well as pneumonia mainly of parasitic or infectious origin. ÖzBu çalışmanın amacı, Endülüs'ün (İspanya) farklı şehirlerinden toplanmış olan barınak köpeklerine ait doku örneklerinde Spesifik Olmayan Reaktif Hepatitin (NSRH) olası nedenlerini araştırmaktı. Hastalık, histolojik olarak, hepatosit nekrozu bulgusu olmadan, karaciğer parankimi boyunca ve portal stroma içinde yayılan lenfositlerin ve plazma hücrelerinin varlığı ile karakterize edildi. İncelenen hayvanlarda, derecesi orta ila şiddetli arasında değişen, spesifik olmayan kronik reaktif hepatit belirlendi. Görülme oranı yönünden değerlendirildiğinde, NSRH ile ilişkili olarak en sık görülen patolojiler gastrointestinal problemler ve böbrek hastalıklarının yanı sıra parazitik veya bulaşıcı kökenli pnömonilerdi. Anahtar sözcükler: Karaciğer, Hepatit, Sokak köpeği, Retrospektif olgular İletişim (Correspondence) +34 92 8457428 Fax: +34 92 8451142
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