Objective: This study investigated the presence of inflammatory response in the dental pulp of rats showing hypersensitive dentin, induced by erosive episodes. Methods: Sixteen Wistar rats were fed with commercial sucrose-free pellet diet for 12 hours; whereas the food was removed during the remainder of the day, and the animals received mineral water or a lemon-based sucrose-free soft drink, according to the group to which they belonged. Eight animals consumed the soft drink to induce hypersensitivity, while the other 8 animals received mineral water (control). After six weeks, the animals were euthanized, the mandible was removed and subjected to a median incision in the sagittal plane, to obtain right and left hemimandibles. The slides stained with hematoxylin-eosin were analyzed using light microscopy. Results: Histological evaluation of the control and experimental groups revealed no inflammatory process in the pulp tissue, and the presence of inflammatory cells, such as lymphocytes, plasma cells, eosinophils and macrophages, was not observed. In addition, there was no edema or dilated and congested blood vessels. The Mann-Whitney test showed no significant difference (p = 1.000) between the experimental and the control groups. Conclusion: In the animal model used, dentin hypersensitivity does not trigger dental pulp inflammatory response. RESUMOObjetivo: Este estudo investigou a presença de resposta inflamatória na polpa dentária de ratos apresentando hipersensibilidade dentinária induzida por episódios erosivos. Métodos: Dezesseis ratos Wistar foram alimentados com ração peletizada isenta de sacarose por 12 horas; enquanto a dieta estava ausente no restante do período diário, os animais receberam água mineral ou um refrigerante dietético à base de limão, de acordo com o grupo ao qual pertenciam. Oito animais consumiram o refrigerante para a indução do quadro de hipersensibilidade, enquanto os demais receberam água mineral (controle). Após seis semanas, realizou-se a eutanásia dos animais, os quais tiveram suas mandíbulas removidas e seccionadas medialmente no plano sagital, a fim de serem obtidas hemimandíbulas direita e esquerda. Lâminas coradas com hematoxilina-eosina foram analisadas sob microscopia óptica. Resultados: A avaliação histológica dos grupos controle e experimental revelou ausência de processo inflamatório no tecido pulpar e também
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