This study shows a relationship between RD and the hs-CRP in patients undergoing hemodialysis. Although the inflammatory state was verified in a large part of the CKD population, patients without RD had more elevated hs-CRP serum levels than those with RD.
orientador, pelos ensinamentos, paciência, atenção e por ter acreditado no projeto e contribuído de forma efetiva para a sua realização.Ao enfermeiro Gilberto dos Reis Machado, pelo incentivo e pela troca de ideias durante a construção do projeto de pesquisa.Aos meus colegas de trabalho da Universidade Federal de Uberlândia, que se esforçaram para suprir minha ausência no setor, no período do meu afastamento.Aos pacientes que participaram do estudo e seus familiares, pela valiosa contribuição.Ao enfermeiro Helton Pereira Lemes, pela parceria durante a coleta de dados. group, whose urinary volume was >100 mL/24 h (n = 33). Demographic information, comorbidity, use of medication, anthropometric data, and blood pressure were analyzed.Serum high-sensitivity C-reactive protein (hs-CRP), and apolipoprotein (Apo) AI and B levels were measured after fasting for 12 h. Urine volumes were collected in a 24 h period during the interdialytic period. Results: Serum hs-CRP levels were higher in the RD-group than in the RD+ group (P = 0.015). In the total group, hs-CRP was significantly correlated with RD (r= −0.25, P = 0.025) and Apo AI (r= −0.25, P = 0.024). A greater proportion of patients had reduced plasma concentrations of Apo AI in the RD-group (31.9%) compared with the RD+ group (9.1%) (P = 0.014). Conclusion: There are relations among a reduction in RD, inflammatory state, and a reduction in Apo AI levels in patients with CKD. Apo AI plays a role in predicting development of inflammatory processes. There is no association of Apo B with hs-CRP or RD.
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