Piroxicam tautomerism was studied in solution. Enol-amide tautomer is presented mainly as a sandwich type dimer in ethanol and DMSO. The addition of water leads to gradual shift of the equilibrium towards the zwitterionic tautomer.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.