Within the last decades, conventional flow cytometry (FC) has evolved as a powerful measurement method in clinical diagnostics, biology, life sciences and healthcare.
An integrated packaging system is developed for the multilayer laminate gas-phase microreactor die whose design and fabrication was described in Part 1 of this series. A commercial plastic socket used for integrated circuit testing was adapted so the reactor chip could be easily installed while maintaining consistent alignment with all electrical contacts. A heated fluidics interface was developed that connects the nonmetallic feed and product gas ports on the microreactor chip to metal tubing. Thermal experiments and 3-D finite-element heat transfer simulations of the combined socket-fluidics assembly showed that the plastic reactor socket could be safely operated up to 250°C. Other tests showed that the microreactor heaters were capable of achieving membrane temperatures in excess of 600°C.Step-response tests demonstrated that temperature changes of ca. 100°C could be achieved in less than 10 ms. Testing of the electrical leads on the reactor chip verified that the device resistance on a single reactor chip was uniform within a few percentage points. The packaged system developed here is used in Part 3 of this series to create a modular reactor board for incorporation into an integrated process system.
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