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Ketamine-assisted psychotherapy is a promising new treatment for a variety of mental disorders of adolescence. There is currently an adolescent mental health crisis, with a high prevalence of disorders, diagnostic complexity, and many adolescents failing to respond to conventional treatments. While there is strong evidence for the use of ketamine in adults for a variety of treatment-refractory mental illnesses, research in adolescents is in its early stages. Ketamine-assisted psychotherapy (KAP) has been described in adults with promising results and here we present the first published cases of the use of KAP in adolescents. The four cases include adolescents aged 14–19 at the initiation of treatment, each with a variety of comorbid diagnoses including treatment-resistant depression, bipolar disorder, eating disorders, anxiety, panic, and trauma-related symptoms. They each initially received sublingual ketamine, followed by sessions with intramuscular ketamine. Their courses varied, but each had symptomatic and functional improvements, and the treatment was well-tolerated. Subjective patient reports are included. Rapid resolution of symptomatology and suffering often occurs within months as the result of the application of KAP to adolescent psychiatric care but is not inevitable. Family involvement in the treatment process appears to be essential to success. The development of this modality may have a singularly positive impact that will expand the psychiatric toolbox and its healing potency.

Screws are often used to connect 3-D printed parts to other objects. When screwing directly into printed plastic, the reliability is limited, and the connection can wear out over time. For more reliable connections, standard metal nuts are often inserted into slots designed into the object. This article presents an approach where nuts and other ferromagnetic components are integrated directly into the part while printing it. Our prototype machine is a modified Prusa-I3 fused filament fabrication printer with an electromagnetic pick and place tool. We introduce augmented slicing software, where the user can insert generic component models from a library and place them at arbitrary positions in the object. Cavities for the components and additional G-code commands for robotic placing are automatically generated and sent to the printer. A printed component tray is attached to the printbed, allowing different part configurations for each print. The pick and place unit is controlled by our OctoPrint plugin OctoPNP. Index Terms-3-D printing, fused filament fabrication (FFF), multimaterial printing, rapid prototyping, smart manufacturing. in computer science (with a minor in oceanography) in 2009, started working with 3-D printers from the University of Hamburg, in 2011, the M.Sc. degree in adaptive slicing algorithms for FFF printing from the University of Hamburg, in 2014, and the Ph.D. degree in computer science from the University of Hamburg, Hamburg, Germany, in 2020, presenting design software for the integration of electronics and sensors into 3-D printed parts. He is currently a Postdoc Research Associate with the Department of Informatics, University of Hamburg. He teaches courses in computer architecture and applied robotics. His research interest is focused on slicing and design algorithms for hybrid additive manufacturing and their application in the field of robotics.