AIM: To determine the relationship between C/C-13910 genotyping and consumption of dairy products in an Uzbek population and to study the incidence of gastrointestinal symptoms for dairy products in the LNP C/C-13910 carriers. METHODS: 100 Uzbeks were examined for nucleotide polymorphisms by polymerase chain reaction/restriction fragment length polymorphism. Dairy tolerance was analyzed by a questionnaire, developed to assess dyspepsia after milk and dairy consumption. RESULTS: The genetic allele variant C/C-13910, the marker of lactase non-persistence, was found in 81% of cases in the Uzbek population. In 19% of the subjects, the genotype C/T-13910 was found. No statistically significant relationship was found between the lactase deficiency genotype and consumption of dairy products (p>0,05). The majority of the participants with the genotype C/C-13910 were reported to consume dairy products every day or several times in week. Among carriers of genotype LNP gastrointestinal symptoms, when consuming dairy products, do not occur more often than in those with genotype LP (p>0.05). CONCLUSION: Despite the high prevalence of lactase deficiency in the Uzbek population, Uzbeks tolerate dairy products well and regularly consume them. Regular consumption of fermented milk products in the diet of the Uzbek population is likely to compensate for the rare use of milk and helps with the intake of calcium and other nutrients contained in milk.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.