Highlights d Neuroblastoma cells comigrate with the neural crest into divergent microenvironments d Neuroblastoma cells can undergo region-specific neuronal differentiation and death d Microenvironment-derived retinoic acid and BDNF are required for differentiation d Cell-autonomous ITSN1-PI3K signaling is required for differentiation, likely via Akt
The focus of this research is to develop and test a new smart glasses application for use in the medical intensive care unit (MICU) to support workflow, patient care, and overall clinical decision-making. The application prototype, mCARE glass, provides clinicians mobility, portability, and hands-free access to real-time patient electronic medical records and bedside data on demand. Five MICU physician volunteers participated in a study consisting of two parts: 1) a usability test with two tasks, and 2) an interview. Part one included usability testing with the use of the tracking pad, followed by the NASA Task Load Index Test and System Usability Scale test. Our findings suggest that mCARE glass has the potential to enhance clinical workflow in the ICU, and that besides providing easy access to patient data, it would improve patient monitoring and surveillance. Participants concurred that for mCARE glass to optimize clinical workflow, it must be well-integrated into one’s daily work as part of decision-making and observation.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.