Exposure dose rate to the tumor and surrounding cells during neutron beam irradiation in Boron Neutron Capture Therapy (BNCT) comes not only from heavy charged particles produced from the 10 B(n,α) 7 Li nuclear reaction, but also from neutron-induced reactions with other biological elements in living tissue, as well as from gamma rays leaked from the reactor core. At Dalat Research Reactor, Vietnam, the neutron and gamma dose rate distribution inside a water phantom were measured by using activation method and Thermoluminescent Dosimeter (TLD) detector, respectively. The results showed that effective thermal neutron dose rate along the center line of the water phantom had a maximum value of 479 mSv h -1 at 1 cm in phantom and then decreases rapidly to 4.87 mSv h -1 at 10 cm. The gamma dose rate along the center line of the water phantom also reach its maximum of 4.31 mSv h -1 at 1 cm depth and decreases to 1.16 mSv h -1 at 10 cm position. The maximum biological tumor dose rate was 1.74 Gy-eq h -1 , not high enough to satisfy the treatment requirement of brain tumors. However, the results of this work are important in supporting of BNCT study in the upcoming stages at Dalat Research Reactor. ABSTRAK Kadar dos pendedahan kepada tumor dan sel sekitarnya semasa pancaran sinaran neutron dalam Terapi Boron NeutronTertawan (BNCT) datang bukan sahaja daripada zarah berat bercas yang dihasilkan daripada tindak balas nuklear 10 B(n,α) 7 Li, tetapi juga daripada tindak balas neutron-teraruh daripada unsur biologi lain dalam tisu hidup, selain daripada sinar gama yang bocor daripada teras reaktor. Di Reaktor Penyelidikan Dalat, Vietnam, kadar pengagihan dos neutron dan gama dalam fantom air diukur masing-masing menggunakan kaedah pengaktifan dan pengesan Thermoluminescent Dosimeter (TLD). Keputusan menunjukkan bahawa kadar dos haba neutron yang berkesan sepanjang garis tengah fantom air mempunyai nilai maksimum 479 mSv h -1 pada 1 cm dalam phantom dan kemudian menurun dengan pantas kepada 4.87 mSv h -1 pada 10 cm. Kadar dos gama sepanjang garis tengah fantom air juga mencapai tahap maksimum 4.31 mSv h -1 pada kedalaman 1 cm dan menurun ke 1.16 mSv h -1 pada kedudukan 10 cm. Kadar dos maksimum tumor biologi adalah 1.74 Gy-eq h -1 namun tidak cukup tinggi untuk memenuhi keperluan rawatan tumor otak. Walau bagaimanapun, keputusan kajian ini adalah penting dalam menyokong pengajian BNCT pada peringkat akan datang di Reaktor Penyelidikan Dalat. Kata kunci: BNCT; fantom air; fluks haba neutron; kadar dos; pengesan TLD
In this research, dose calculation and measurement from B10 (n, α) Li7 reaction usingfiltered neutron beam at the Nuclear Research Institute have been reported. Calculation was carried out by Monte Carlo method using MCNP5 code. Neutron activation technique using vanadium foil was employed to determine neutron flux at various positions in phantom from which neutron dose has been calculated using conversion factor. These calculations are basics for the dose determination research of the Boron Neutron Capture Therapy (BNCT) in Vietnam.
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