This study examines the length of the estrous cycle in 16 Sambar deer hinds in National zoological gardens in Dehiwala and Kegalle, Sri Lanka (NZGDK) assessed with the use of changes in progesterone concentrations, along with the changes in the profile of this hormone and by the visual estrus manifestations. The objectives of the present study were to characterize ovarian activity throughout the estrous cycle and the non-pregnant luteal phase of captive sambar deer in Sri Lanka. These objectives were achieved with the use of radioimmunoassay (RIA) to measure fecal concentrations of progesterone and visual estrus manifestation. Fecal samples were collected from non-pregnant sambar deer hinds (aged 2–4 years)over the period of six months on daily basis, both during breeding and non-breeding seasons. Estrous cycles were recorded in non-pregnant females, based on fecal progesterone concentrations. The average estrous cycle length was 26.1±2.08 days (mean ± SEM) and 2.10 ± 0.51 days in the inter-luteal phase.The average fecal progesterone concentrations attained the peak mid-luteal values of 2.74 ng mL–1. There appeared to be variation in fecal progesterone amplitude between animals and between dates, but the low frequency of sampling prohibited confirmation of trends. Behavioral estrus was detected only when the average progesterone concentrations were less than 0.07 ng mL–1. However, not all periods of depressed progesterone secretion were associated with the observed estrus. Behavioral estrus was detected in hinds when progesterone concentrations were less than 0.07 ng mL–1; a subsequent rise in progesterone indicated ovulation taking place at this time.
Introduction and Background: The outcome of radioiodine therapy is influenced by factors such as age, gender, goitre size, severity of hyperthyroidism and radioiodine uptake and turnover among the hyperthyroid patients. Objective: This study aimed to identify the correlation between Free T4 values at diagnosis and 03, 06 months after fixed dose radioiodine therapy among the hyperthyroid patients. Methodology: This was a prospective observational study. 57 Patients, after 10 mCi fixed dose radioiodine therapy for hyperthyroidism were followed up at 03, 06 months intervals at Nuclear Medicine, Peradeniya during the period of years 2018 and 2019. The details on base line clinical presentation, Free T4 levels and the clinical status after the radioiodine therapy were collected using a check list. Data was analysed using the SPSS version 25 by using Pearson's correlation and independent sample t-test. Results: There were 70.2% of Graves' disease patients and 29.8% of toxic multi nodular goitre patients among the 57 patients. The Pearson's correlation showed a weak relationship between the Free T4 value on diagnosis and 03 months after radioiodine therapy (r=0.475, P=0.003) and a moderate relationship between the Free T4 value on diagnosis and 06 months after the radioiodine therapy (r=0.644, P<0.001). The independent sample t-test showed that the patients who were hyperthyroid 06 months after radioiodine therapy had significantly high (P=0.009) mean Free T4 (8.64ng/dl) on diagnosis compared with the patients who were euthyroid or hypothyroid 06 months after radioiodine therapy (mean Free T4 value on diagnosis 4.77ng/dl). Conclusion: This study has found a correlation between the Free T4 value on diagnosis and the Free T4 value 03, 06 months after radioiodine therapy and the Free T4 level on diagnosis can be used as a predictor for the outcome of radioiodine therapy.
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