Results from the ARC confirmed a frequency of 1 in 546 in the CBS' blood donor population for severe IgA deficiency (<0.05 mg/dL), 1 in 840 for those without anti-IgA, and 1 in 1560 for those with antibody. Donors repeatedly confirmed as severely IgA deficient without anti-IgA were considered eligible for the CBS IgA-deficient donor registry program.
Forty-eight recipients of blood from donors who subsequently tested positive for HIV were identified in a low-prevalence area. Active lookback and traceback programs linking a transfusion service and an HIV clinic were successful in identifying infected recipients.
Haemovigilance systems (HSs) have been established in many countries (see Vox Sang 2006; 90: 207-241). The main purpose so far has been the registration of all incidents and untoward effects related to blood transfusion. However, the question has arisen whether the optimal use of blood should be included in the HS. For this international forum, information was obtained on the opinion of the relevant authorities concerning this aspect of haemovigilance and how it should be organized. To obtain this information, the following questions were sent to representatives in the various countries.
The 14 WNV donor samples detected by routine screening were confirmed as WNV RNA-positive by a WNV RNA-specific in-house assay and by demonstration of seroconversion in 13 of the 14 donors.
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