The higher prevalence and variety of clinical manifestation of disorders of falling asleep and sleep maintenance (insomnia) in persons of able-bodied age condition necessity of development of personified prevention programs subject to main pathophysiologic mechanisms conditioning risks of development of sleep disorders and related to them somatic diseases. Purpose of study. To analyze functional state of brain and cerebral blood flow in brain workers with higher level of professional stress and sleep disorders and to determine risk factors of development of established disorders for scientific substantiation of preventive activities. Material and methods. The examination was applied to two groups of brain workers with higher level of work intensity (class 3.3) and professional stress. The main group included 77 individuals stated availability of insomnia (index of insomnia severity 20.4±3.1 points). The control group included 88 individuals without significant sleep disorders. The clinical instrumental examination was implemented including questionnaire survey, night polysome graphic analysis, electroencephalography (EEG) and rheography analysis. Results. The high level of professional stress in workers with sleep disorders was statistically related to decreasing of efficiency of total time of sleep, decreasing of slow-wave sleep шт its structure, increased sleep fragmentation due to increasing of reactions of EEG-activation (r=0.35). The study of cerebral blood flow established that in 50% of individuals with sleep disorders and 32% of individuals without sleep disorders the instability of vascular tone was registered. According data of prospective observation, the signs of sleep disorders continued in 92% of patients with non-specific alterations of EEG with predominance of low-amplitude high-frequency activity and in 65% of patients with absence of similar alterations. The detected alterations can be considered as markers of condition of increased reactivity of central and vegetative nervous system being predisposing factor of changing from acute or transitory insomnia to chronic form.
The authors present results of study concerning risk factors of sleep initiation and maintenance disorders in mental workers residing in Moscow — governmental institutions staffers and medical workers. To evaluate insomnia severity, the authors used questionnaire «Index of insomnia severity», studied work conditions and work-related stress intensity. The study results prove leading role of work intensity and stress at work in sleep disorders formation. The governmental employees demonstrated positive correlation between integral parameter of work intensity and insomnia severity index (r=0.43). Findings are that work-related stress which was evaluated via psycho-social characteristic of work increases insomnia risk (OR=2.3). Among environmental factors, the maximal role in insomnia formation is played by acoustic factor (OR=1.41). Moreover, somatic disorders were statistically connected with insomnia (OR=1.3). Shares of separate risk factors of chronic insomnia appeared to be age-related. The data obtained enable to optimize complex of measures to prevent chronic insomnia in workers.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.