197 preoperative preparation, surgical implement and postoperative evaluation. All the clinical data were collected. Results: In the past five years, 3D printing technique was used in 27 clinical cases which microvascular free flap was used to reconstruct oral and maxillofacial defect. In our study, rapid prototyping 3D printing models were used to simulate the tumour ablation and evaluate the defect extension in 14 cases. In another 10 cases, 3D printed surgical templates were printed according to the preoperative digital design. For the third part, patient-specific maxillofacial implant were printed using 3D printing technique in three cases. All of the free flaps were survived and the final reconstructed results were satisfied in all patients. Conclusion: 3D printing technique had promising implication in oral and maxillofacial reconstruction. Preoperative rapid prototyping 3D printing model could be used to predict the extension of defects, simulate the reconstruction operation and prefabricated titanium mesh or plate. 3D printed surgical template was helpful for the accurate implementation of surgical plan.3D printing patient-specific implants were very useful to reconstruct complex 3 dimensional defects and obtain the best reconstructive result.
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