S23orphan drugs. Quality of life data seems to be a more critical outcome for OOD in the 3 countries. CONCLUSIONS: Despite less compelling evidence and substantial trials limitations, OODs achieve similar HTA recommendation as non-OODs in France suggesting a more flexible attitude in the deliberative process. Similar findings in Germany are driven by mandatory additional benefit for ODs. While in Canada, OODs achieve a lower positive recommendation than non-OOD suggesting a more strict deliberative process.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.