Introduction: Ovarian tumors account for fifth most common cause of cancer related death in females involving a variety of histological diagnosis. It accounts for 6% of all cancers. Though it is one of the treatable cancers due to its sensitivity to anticancer therapies, it frequently does not result in symptoms until the cancer has spread extensively. Objectives: To study the incidence, histopathological spectrum and clinical correlates of ovarian tumours at B.P. Koirala Institute of Health Sciences (BPKIHS). Methods: A cross-sectional study was undertaken during a period of one year (1
This is an analysis of the incidence of molar pregnancies and those of complete and partial molar pregnancies across the reproductive age range for BP Koirala Institute of Health Sciences (BPKIHS) in the period 2010-2011.Patients with molar pregnancies registered with BPKIHS from January 2008 to January 2010 were identified. The overall number of molar pregnancies registered was compared to the number of maternities (live births and still births) and total viable conceptions for this year. A retrospective study of 64 cases of molar pregnancies recorded at BPKIHS during the two year time was done. Medical records were reviewed. Incidence, clinical presentation and methods of diagnosis were studied.During the study period, there were 37 complete moles, 23 partial moles, 1 persistent gestational trophoblastic tumor, 1 choriocarcinoma, and 2 invasive moles. The incidence of molarpregnancy was 3.94 per 1000 deliveries. Median distribution was at 22 years of age, and majority (67%) presented during early second trimester. Twenty one (32.8%) women were of blood group A positive and ten (15.6%) presented with severe form of anemia.This study provides detailed data regarding the incidence of partial and complete molar pregnancies with increasing maternal age. It confirms the relation of molar pregnancy with age, and blood group. Complete mole had the highest incidence, affecting mostly younger age group, and usually in the first half of their pregnancy. KEY WORDS gestational trophoblastic disease, hyaditiform mole, persistant gestational tumorsThis study presents the incidence of molar pregnancy, including its signs and symptoms in Terai belt of Nepal which constitute a sub-tropical climate and rural to suburban living standard. METHODSThis was a retrospective descriptive study conducted at
Objective: To compare intramyometrial, intramuscular (I M) 15 methyl PGF2α with IM Methergin on the duration and blood loss of 3rd and 4th stage of labor. Method: Prospective randomized control study, done from May 2004 to June 2005. Three hundred parturient women were randomly assigned to receive either an intramyometrial or IM 15 methyl PGF2α or IM methergin immediately after delivery of baby. Duration of 3rd stage and blood loss during 3rd and 4th stage of labor was measured. Other parameters measured were – presence of atonic postpartum hemorrhage (PPH), need for MRP, and blood transfusion, any side effects of drugs. Results: Women who received prophylactic intramyometrial PGF2α had significantly shorter duration of 3rd stage of labor (2.3 + 0.66 mins: p= 0.0000) compared to both IM group ( 3.04+1.03 mins) and IM methergin group ( 4.22+ 1.58 mins) and also significantly less blood loss ( median- 110ml; P= 0.0002) compare to both IM group (median-145ml) and IM methergin group( medin-197ml). Conclusion: Intramyometrial PGF2α is better than IM PGF2α and methergin in terms of reducing duration of 3rd stage and blood loss. Thus can be prophylactically used especially in those patients where even minimal blood loss will adversely affect the health of mother. DOI: http://dx.doi.org/10.3126/njog.v3i2.10829 Nepal Journal of Obstetrics and Gynaecology Vol.3(2) 2008; 35-39
Background: Mast cells are heterogeneous group of immune cells involved in multiple biological events. The significance of mast cells in uterine tumor surveillance has been studied with conflicting results. The presence of mast cell in tumor has been described as evidence of a host immunologic anti tumor response and if they are abundant the prognosis is good. However in other studies, with the help of different granules of mast cell, it is said to be very closely related with angiogenesis and tumor invasion. The study aims to analyze the histomorphologic changes with special reference to mast cells in different neoplastic and non neoplastic disease of uterine cervix, and also the relationship of the mast cell population with degree of anaplasia and mitotic figures.Materials and methods: Cervical biopsies received in the department of Pathology for HPE were stained with H& E stain and toludine blue for the identification of mast cellResult: Out of a total of 100 cases, 82 were non neoplastic cases with the mean mast cell count of 83.73 and mean age of patient being 44.30 year. Eighteen neoplastic cases were included which had mean mast cell count of 13.5 and mean age of 49.5 year.Conclusion: Mast cell was found to be highest in non Neoplastic lesion with increase count in polypoidal cervicitis. There was a statistical significance variation between mast cell count in neoplastic and non Neoplastic disease of the cervix. However,role of age in mast cell count was least significant.DOI: http://dx.doi.org/10.3126/jpn.v4i8.11594 Journal of Pathology of Nepal; Vol.4,No. 8 (2014) 658-662
Background: Birth is a major challenge for the newborn to negotiate successfully from intrauterine to extra uterine life. The fi rst few hours since birth is the most crucial period in the life of an infant for further growth and development, which is largely determined by the quality of care that the newborn receives. Objective: The aim of this study is to assess the quality of care provided by nursing personnel to newborn in the labour room. Materials and methods:This study was conducted in BP Koirala Institute of Health Science. Cross sectional, non participatory observational research design was adopted for the study. Care provided by nursing personnel to 814 normal newborns was observed. Samples were chosen by non probability purposive sampling technique. Data was collected through observational method by trained nursing personnel, using 46 items pre-tested, validated and self developed observational checklist. Care provided to newborns was observed from birth to two hours and categorised as good, average and poor based on scores obtained. Data was entered and analysed using SPSS-10. Descriptive statistics-[Mean, percentage, frequencies and standard deviation] was used to describe the quality of care provided to the newborn babies.Results: Overall quality of care was good in 42.36%, average in 57.64% and none of them received poor care. Overall mean score for quality of care was 34.75/46 (75.54 %). Regarding subscales quality of care was good in majority of newborns in areas such as Preparation to receive the baby (76.1%), Initiation of breathing (100%), Maintaining thermoregulation (77.3%), Physical assessment (90.9%), and other aspects of care (95.2%). However the quality of care was poor in majority of newborns in establishment of breast feeding (58.23%) and average in prevention of infection (76.9%). Conclusion: Study fi ndings highlight the need for focus in establishment of breast feeding and prevention of infection.Key words: Quality of care, newborns, nursing personnel, breast feeding, prevention of infection and assessment of newborn.
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