Pathologies associated with spinal cord injury are some of the leading diseases
in the world. The search for new therapeutic agents and 3D
biodegradable materials for the recovery of spinal cord functions is a
topical issue. In this review, we have summarized the literature data on the
most common experimental models of spinal cord injury in laboratory
rats and analyzed the experience of using 3D biodegradable materials
(scaffolds) in experimental studies of spinal trauma. The advantages
and disadvantages of the described models are systematically analyzed
in this review.
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