Fibro-calcified nodules represent a rare group of lesions that are composed of fibrous connective tissue with calcified areas. The etiology of fibro-calcified nodules may be related to secondary changes that are caused by trauma, infectious and autoimmune diseases, or calcified thrombi. The purpose of this paper is to report the presence of a lesion of a fibro-calcified nature in the masseter muscle and its possible etiologies. The patient, a 35-year-old melanoderm female, presented with a nodule in the left masseter region with 12 months of progression. Considering the accessibility of the lesion, an excisional biopsy was performed. A histopathological examination revealed residual fibro-calcified nodules with central foci of coagulation necrosis surrounded by fatty tissue and striated skeletal muscle fibers. The test for acid-alcohol-resistant bacillus (BAAR) was negative. Two years after the surgical procedure, there were no signs of lesion recurrence. Thus, the results of histochemical staining ratified the fibro-calcified aspect of the lesion, which suggested dystrophic calcification.
ResumoO osteossarcoma é considerado o tumor ósseo mais comum em cães, acometendo principalmente o esqueleto apendicular de animais adultos ou idosos, com idade média de sete anos. A etiologia do osteossarcoma apendicular canino permanece desconhecida. Alguns fatores predispõem os animais ao surgimento da neoplasia, incluindo: tamanho, raça e família. A neoplasia pode ser classificada pelas características macroscópicas e radiológicas em simples, composta ou pleomórfica. O presente artigo é um relato de caso de osteossarcoma do tipo composto com metástases em pericárdio, pulmão, pleura, músculos intercostais, fígado e rim em uma cadela de raça Labrador Retriver. Neste, apresenta o histórico do animal, que em conjunto com os achados necroscópicos e o exame histopatológico confirmaram a causa da morte. Conclui-se que o exame histopatológico é importante para classificar o tumor dependendo do padrão celular e para identificar a presença de metástase nos diferentes órgãos coletados.Palavras chaves: Tumor ósseo, metástase, cão, exame histopatológico. AbstractOsteosarcoma is considered the most common bone tumor in dogs, usually affecting the appendicular skeleton of animals adults or seniors with an average age of seven years. The etiology of canine appendicular osteosarcoma remains
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