In human medicine the Sequential Organ Failure Assessment (SOFA) score is one of the most commonly organ dysfunction scoring systems used to assess critically ill patients and to predict the outcome in Intensive Care Units (ICUs). It is composed of scores from six organ systems (respiratory, cardiovascular, hepatic, coagulation, renal, and neurological) graded according to the degree of the dysfunction. The aim of the current study was to describe the applicability of the SOFA score in assessing the outcome of critically ill dogs. A total of 45 dogs admitted to the ICU was enrolled. Among these, 40 dogs completed the study: 50 % survived and left the veterinary clinic. The SOFA score was computed for each dog every 24 hours for the first 3 days of ICU stay, starting on the day of admission. A statistically significant correlation between SOFA score and death or survival was found. Most of the dogs showing an increase of the SOFA score in the first 3 days of hospitalization died, whereas the dogs with a decrease of the score survived. These results suggest that the SOFA score system could be considered a useful indicator of prognosis in ICUs hospitalized dogs.
Multiple organ dysfunction syndrome is defined as the presence of altered organ function in an acutely ill patient such that homeostasis could not be mantained without intervention. It is reported that mortality rate in humans with 4 organ systems failing reaches nearly 100%, while there are few publications documenting this syndrome in dogs. To the author's knowledge, this is the first report that describes the clinical manifestations and the favourable outcome to intensive medical care in a dog with Klebsiella pneumoniae septicemia and multiple organ dysfunction with 6 organ systems failing. Derangement of cardiovascular, respiratory, gastrointestinal, pancreatic, renal and coagulation system developed. This dog manifested reversible myocardial depression that is a common complication of sepsis in people but it is rarely reported in dogs.
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