Objectives: To determine healthcare resource use and costs in patients with acute heart failure (AHF) and chronic heart failure during for 12 months in a Spanish population-based setting. Methods: A retrospective observational study was made based on review of records of patients aged $40 years who requested care. Two study groups were identified (AHF yes/no). Main measurements: comorbidity, clinical variables (functional class, aetiology), metabolic syndrome (MS) and mortality. The cost model included direct/indirect health costs. The statistical analysis was made using multiple regression models, and statistical significance was p ,0.05. Results: We included 1,204 patients (prevalence: 4.1%, mean age: 73.3 years, 53.4% female): 72.0% had high blood pressure, 49.8% dyslipidaemia, 36.9% diabetes and 35.1% atrial fibrillation and 38.5% (N = 464) had $ 1 episode of AHF. AHF patients had a higher proportion of NYHA III-IV (52.1% vs. 38.8%, p = 0.002), MS (50.3% vs. 45.4%, 0.052) and mortality (15.6% vs. 7.0%, p ,0.001). The total cost of AHF was V 10,591 vs. V 4,544 for chronic heart failure (p ,0.001).
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