A mathematical model, coupling the dynamics of short-term stem-like cells and mature leukocytes in leukemia with that of the immune system, is investigated. The model is described by a system of seven delay differential equations with seven delays. Three equilibrium points E0, E1, E2 are highlighted. The stability and the existence of the Hopf bifurcation for the equilibrium points are investigated. In the analysis of the model, the rate of asymmetric division and the rate of symmetric division are very important.
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