Objective. The aim of this study was correlation of skin adnexal tumors with age, sex, and location and determining its incidence in the Department of Pathology at Dr. D. Y. Patil Medical College and Hospital, Kolhapur, Maharashtra. Material and Methods. 56 cases were included in this study from Jan 2004 to June 2010 with respect to incidence of adnexal tumors, age, and sex distribution. All slides were stained with haematoxylin and eosin and then findings were corroborated with special stains like PAS and reticulin wherever required. Results. 80.36% (45/56) were benign and 19.64% (11/56) were malignant adnexal tumors. The sweat gland tumors constituted the largest group (42.86% 24/56) cases followed by the hair follicle tumors (35.71%, 20/56) of cases and sebaceous gland tumors (21.43%, 12/56) cases. Overall male : female ratio was 1.07 : 1. The commonest age group was 51–60 years and the commonest affected body part was head and neck region (64.28%, 36/56) followed by trunk (14.28%, 8/56). Clear cell hidradenoma and pilomatricoma were commonest benign tumors and sebaceous carcinoma was the only malignant tumor seen. Conclusion. The incidence of benign skin adnexal tumors was more as compared to the malignant tumors. Malignant tumors were seen in older age group, usually over 50 years of age.
Estimation of age of a person, whether living or dead, is vexing problem for medical jurist. 1 The duty of Forensic medicine knowledge expert is not only to examine dead bodies but also to give his opinion in living individual for solving various medico-legal problems like determination of age, identification, sexual assault, sterility, impotency, pregnancy, criminal abortion, disputed paternity, alcoholic intoxication etc. Skeletal age, dental age, morphological age, secondary sex character age are other method in use for asserting age of individual. In medico legal practice a combined view is taken and opinion is expressed after considering all methods. However radiological examination is a must and the court of law did not believe any conclusion without it. 2 AIM AND OBJECTIVES: An extensive work has been carried out on the theme in different states of India and abroad as well. However, very little work has been reported with reference to Agra (U.P.) population so the present study was conducted on Agra region population to study union of lower end of humerus for estimation of age. MATERIAL AND METHODS: This study was carried out in 100 males and 100 females between the age group of 10-20 years of normal healthy individuals whose exact date of birth was known were included in the study and the cases were collected from college and institutions by obtaining the permission from their head of the institution. In all cases right side is Xrayed (AP and Lateral view). RESULTS: It is clear from the observations that fusion of different ossification centers occurs 2-3 year earlier in female subjects as compared to male subject studied. It was found from the study that in females at the of 16 years all the epiphysis of lower end of humerus are fused. Medial epicondyle is the last epiphysis to fuse at lower end of humerus in both male and female. In male all epiphysis of lower end of humerus are fused except medial epicondyle at age of 16 years. The sequence of fusion at lower end of humerus was almost similar with other workers, however the range varied which can be attributed to many among other reasons i.e. geographical variation, nutritional factors etc. As no statistical tests were applied in present study that is also with relatively smaller sample size, we would feel to suggest larger study with statistical methods for incorporating the observations of present study as regional database.
Angiosarcoma is rare and constitutes < 1% of all malignant bone tumours. A seventy two year male presented with pain and soft tissue swelling around L4 vertebral body compressing nerve root. An uncomplicated biopsy of lesion was performed and a initial diagnosis of angiosarcoma was considered, further confirmed by immunohistochemistry. We here in report a rare case of angiosarcoma of bone with brief review of literature .
ABSTRACT:In the present study, thirty patients in the age range of 22 to 63 years of age were included after being diagnosed to be having brain tumour on CT scan or conventional MRI. In addition DWI, MRS, and PWI were carried out in these patients. All the patients with suspicious malignant lesions were then subjected to FDG-PET examination. Histopathological correlation was obtained in all the patients to serve as gold standard against which other modalities will be assessed for their sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy. Out of thirty patients selected for this study, twenty cases were found to be malignant and ten cases were benign on Histopathological evaluation. Majority of malignant lesions were glioblastoma multiforme. Amongst benign cases, majorities were meningioma, one was a Granulomatous lesion and one was a benign cystic lesion. MRI including the novel techniques showed high sensitivity and specificity in identifying malignant brain lesions and has a future role in better characterization of brain tumours. Wherever available, it should be integrated in routine workup of patients presenting with brain tumours or for follow up of patients undergone surgery / adjuvant chemotherapy.
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