A33ies, 432 symptom concepts (range 7-33, M= 16.6 [SD] 6.4) were elicited. Each sample was divided into quartiles based on the chronology of individual interviews. Study results (i.e., patient reports) were then reviewed to determine the interview number and quartile in which each concept was first elicited. Results: Analysis showed that 84.0% (n= 363), 92.4% (n= 399), 97.2% (n= 420), and 99.3% (n= 429) of all elicited concepts had emerged by the tenth, fifteenth, twentieth, and twenty-fifth interview, respectively. Less than 1% (n= 3) of concepts emerged after the 25thinterview in samples with > 25 subjects. ConClusions: While a variety of factors inform sample size decisions in concept elicitation interview studies, this analysis suggests that researchers can reasonably expect to elicit 95% to 100% of the targeted disease-related symptoms-level concepts, and thus achieve saturation, through the conduct of 20 to 25 interviews.
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