Cryptolepine (1), a 3 : 4-benz-ô-carboline derivative, was synthesized (1) and then isolated from Cryptolepis triangularis (2) several years ago. In 1978, Dwuma-Badu and others (3) isolated cryptolepine from the roots of the West African plant Cryptolepis sanguinolenta (Lindl.) Schlecter, which began a whole new series of investigations into the constituents of C. sanguinolenta. Biological evaluation (4) of cryptolepine confirms the use of the plant as an antimicrobial agent (5) by West African natives. Cryptolepine also has reported hypotensive (6), antipyretic
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.