As many World War II and Korean Conflict veterans suffering from posttraumatic stress disorder (PTSD) grow older, increasing numbers will be diagnosed with dementia. We retrospectively analyzed patients with dementia, comparing the behavioral disturbances of those with PTSD to those without PTSD. We hypothesized that due to the additive effect of the neurobiological and behavioral changes associated with PTSD and dementia, the dementia with PTSD group would show more agitation and disinhibition than the dementia without PTSD group. Sixteen patients with diagnoses of dementia and PTSD were matched on age and Mini-Mental States Examination (MMSE) scores to 16 patients with dementia without PTSD. Demographic characteristics, co-morbid diagnoses, global Assessment of Functioning (GAF), Cohen-Mansfield Agitation Inventory (CMAI), and paranoid items of Brief Psychiatric Rating Scale (BPRS) and Positive and Negative Syndrome Scale for Schizophrenia (PANSS) were assessed. The patients with diagnoses of dementia with PTSD did not differ significantly in their clinical presentation, hospital course, and condition at discharge from patients with dementia without PTSD. Chi-square analysis showed that significantly more subjects in the PTSD group were prescribed anti-depressants compared to the non-PTSD group. Interestingly, within the PTSD group, the subgroup of patients who were former prisoners of war had a significantly higher mean score for paranoia and significantly less verbal agitation. This pilot study reveals that a diagnosis of PTSD alone is not sufficient to influence behavior in veterans with dementia; however, we also present provocative results that patients with more severe trauma (POW) do have changes in their behavior.
This study evaluated the separate and additive contributions of direct violent victimization, witnessed violence, and community chaos to children's posttraumatic stress reactions and behavior problems. Participants were 181 African American youths residing in low-income urban communities. Regression analyses revealed direct victimization to be most predictive of behavior problems and community chaos most predictive of posttraumatic stress reactions in children. Path models established community chaos as a mediator of the relation between witnessed violence and posttraumatic stress reactions and the relation between witnessed violence and behavior problems. Community chaos did not mediate the relation between direct victimization and posttraumatic stress reactions or behavior problems; however, a significant direct contribution of violent victimization to behavior problems was established. Findings support the emphasis placed on community chaos and instability in exacerbating stress reactions in the presence of interpersonal violence. Findings are discussed in terms of risk minimization and distress management.
Objective Cross‐cultural differences in treatment and diagnosis exist in several psychiatric disorders. This study examines phenomenological and treatment differences between Caucasian and African‐American patients presenting to a geropsychiatric unit for treatment of behavioral disturbances associated with dementia. Methods One hundred and forty‐one Caucasian patients were compared to 56 African‐American patients consecutively admitted to a VA geropsychiatric inpatient unit. At admission, differences in behavior disturbances between the two groups were examined using the Mini‐Mental State Examination (MMSE), Cohen‐Mansfield Agitation Inventory (CMAI), Hamilton Rating Scale for Depression (HAM‐D), Brief Psychiatric Rating Scale (BPRS) and the Positive and Negative Syndrome Scale for Schizophrenia (PANSS). Differences in treatment were assessed by comparing medication types and doses between the two groups. Results and Conclusion Results showed that Caucasian and African‐American patients with dementia and behavioral disturbances presented and responded similarly to like treatment on an inpatient geropsychiatric unit. The similarity between the two groups may be explained by the multi‐ethnic make‐up of the interdisciplinary treatment team and by the use of standardized scales to measure symptomatology and response. Copyright © 1999 John Wiley & Sons, Ltd.
The atypical antipsychotics are gradually becoming the mainstay of treatment for psychosis in the elderly. The present study examines the effectiveness and tolerability of risperidone and olanzapine treatment in 34 matched male patients admitted to a VA Medical Center geriatric inpatient unit. The Positive and Negative Syndrome Scale for Schizophrenia (PANSS), the Cohen‐Mansfield Agitation Inventory (CMAI), the Rating Scale for Side‐Effects, the Extra‐Pyramidal Rating Scale, and the Mini‐Mental State Examination were administered at admission and discharge. T‐tests at admission and discharge across groups indicate that the patients as a whole were performing significantly better following their stay on the CMAI (t(30)=4.31, p=0.000), the GAF (t(31)=9.73, p=0.000), the PANSS total score (t(29)=3.82, p=0.001), and the positive symptom portion of the PANSS (t(28)=4.29, p=0.000). No significant differences were detected between the two groups with regard to length of hospitalization, or reduction in scores on the PANSS, or CMAI, however the daily cost of risperidone was 1/3 as much as olanzapine (p=0.00). The two treatments were comparable in the elderly men evaluated in this study. Copyright © 2001 John Wiley & Sons, Ltd.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.