We successfully demonstrated two different reaction pathways for the synthesis of β-aryl-γ-lactam and 2-oxo-1,2-dihydroquinoline derivatives using β-nitrostyrenes. The reaction strategy involves the Michael addition followed by reduction and cyclization reactions. Michael adducts containing two different nitro group such as one on aryl ring and another on side chain, selectively takes the path to involve nitro group on aryl to form 2-oxo-1,2dihydroquinoline derivatives as cyclized product. Michael adducts with nitro group on side chain alone forms β-aryl-γ-lactam derivatives as cyclized product. This methodology is appealing with reliability and scalability with gram scale products that can be synthesized. These heterocyclic compounds can be exploited for their biological activity.
Der Ni‐Komplex (I) reagiert mit Gallussäure unter Ersatz des Äthylendiamins zu dem Komplex (II), ‐in dem das Äthylendiamin in der äußeren Sphäre als Äthylendiammonium erhalten bleibt.
Die Reaktion von Brenzcatechin, 2,3‐Dihydroxynaphthalin und Pyrogallol mit den Bis‐[diamin]‐kupfer‐ und ‐nickel‐Komplexen führt zu den Komplexen (I), deren Bildungskonstanten bestimmt werden.
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