The endogenous, peptide ligand for the orphan receptors GPR7 and GPR8 was identified to be neuropeptide W (NPW). Because these receptors are expressed in brain and in particular in hypothalamus, we hypothesized that NPW might interact with neuroendocrine systems that control hormone release from the anterior pituitary gland. No significant effects of NPW were observed on the in vitro releases of prolactin (PRL), ACTH, or GH when log molar concentrations ranging from 1 pM to 100 nM NPW were incubated with dispersed anterior pituitary cells. However, NPW, when injected into the lateral cerebroventricle of conscious, unrestrained male rats, in a dose-related fashion elevated PRL and corticosterone and lowered GH levels in circulation. The threshold dose for all three effects was 1.0 nmol. We conclude that endogenous NPW may play a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland but does not itself act as a true releasing or inhibiting factor in the gland. Central administration of NPW23 also stimulated water drinking and food intake. The ability of exogenous peptide to decrease GH but stimulate PRL secretion and activate the hypothalamo-pituitary adrenal axis, together with the observed behavioral effects, suggests that endogenous NPW may play a role in the hypothalamic response to stress.
Now more than ever companies are expecting students graduating from baccalaureate engineering degree programs to have both strong technical problem solving skills and a level of business expertise. With corporate investment and engineering project funding decisions becoming increasingly reliant upon company financial statement and stock price impact,
pursuing an Integrated M.S./B.S. Degree in Industrial Engineering with a minor in Six Sigma Methodology. As a Schreyer Honors Collegr scholar, she is writing her thesis in Engineering Education, specifically from a Learning Styles perspective. In the summer of 2013, Cyndy interned with the Walt Disney Company in the Workforce Management Department. As an intern, she was able to create a Variance Analysis Tool to monitor workload forecasting for the Walt Disney World resort. Miss Jennifer Louise Mines, The Pennsylvania State University Jennifer is a 2013 graduate of The Pennsylvania State University with a Master's degree in Industrial Engineering. Her Master's thesis examined undergraduate student satisfaction regarding Industrial Engineering education. Jennifer received her Bachelor's degree in Mathematics and certification in Secondary Education at Misericordia University. She is a certified Mathematics teacher for grades 7-12 in the state of Pennsylvania. She currently works in consulting as an analyst at Accenture.
pursuing an Integrated M.S./B.S. Degree in Industrial Engineering with a minor in Six Sigma Methodology. As a Schreyer Honors Collegr scholar, she is writing her thesis in Engineering Education, specifically from a Learning Styles perspective. In the summer of 2013, Cyndy interned with the Walt Disney Company in the Workforce Management Department. As an intern, she was able to create a Variance Analysis Tool to monitor workload forecasting for the Walt Disney World resort. Miss Jennifer Louise Mines, The Pennsylvania State University Jennifer is a 2013 graduate of The Pennsylvania State University with a Master's degree in Industrial Engineering. Her Master's thesis examined undergraduate student satisfaction regarding Industrial Engineering education. Jennifer received her Bachelor's degree in Mathematics and certification in Secondary Education at Misericordia University. She is a certified Mathematics teacher for grades 7-12 in the state of Pennsylvania. She currently works in consulting as an analyst at Accenture.
Now more than ever manufacturing in the United States needs a workforce with a blend of both strong hands-on trade skills and the technical problem solving skills typically learned through the completion of a Bachelor of Science in Industrial Engineering program. This paper discusses a holistic approach being taken in an industrial engineering program to increase student interest in manufacturing by providing a hands-on educational experience in a manufacturing processes course while providing ample opportunities for students to gain hands-on manufacturing work experience through undergraduate teaching internships and manufacturing co-ops and internships.The research shown in this paper discusses the active role that senior undergraduate students with manufacturing internship and co-op experience play in helping to deliver the manufacturing processes course. Senior undergraduate industrial engineering students with manufacturing industry internship or co-op work experience have been helping to deliver a manufacturing processes course through hands-on lab instruction, on site plant visits, industry speakers and networking sessions, and a final course case study.The paper displays the results of a questionnaire that included a blend of qualitative and quantitative questions administered to the junior and senior level industrial engineering students completing the manufacturing processes course. In addition to data collected on student satisfaction and motivation with course delivery, the survey also collected data inquiring prior student knowledge of manufacturing processes, perception of manufacturing, and student interest in manufacturing careers before and after taking the manufacturing processes course. The survey also inquired on student internship and co-op trends for the industrial engineering students completing this manufacturing processes course. Background and MotivationThe manufacturing industry is still a significant and viable career opportunity for industrial engineers in the United States of America (USA). In 2013, the manufacturing industry accounted for 12% of the Gross Domestic Product (GDP) for within the United States 1 . Furthermore, for every $1.00 spent in manufacturing, another $1.37 is added to the economy, which is the highest multiplier effect of any industry 2 . In 2013, there were approximately 17.6 million jobs in the USA that the manufacturing industry directly supported 3 . Also in 2013, the average manufacturing worker earned $77,506 in salary and benefits, which is an increase of 24% over the average worker in all industries ($62,546) 4 . By itself, the manufacturing industry sector in the USA would be the 9 th largest economy in the world 5 .Unfortunately, a number of future engineers have learned or developed incorrect assumptions and stereotypes regarding the manufacturing industry. Students are under the impression that manufacturing is a floundering industry in the USA and there are limited jobs and limited job growth potential. However, this is an incorrect, and p...
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