Almost the same clinical outcomes can be achieved with and without duroplasty. There might be an option to perform duroplasty if simple procedure fails.

No abstract

These results demonstrate, for the first time, that the polyamine interconversion pathway has an important role in the increase of putrescine levels after TBI and that the polyamine oxidase inhibitors, blockers of the interconversion pathway, can be neuroprotective against edema formation and necrotic cavitation after TBI.

No abstract

Dexamethasone has no significant effect on the volume of peritumoral edema in glial tumor and metastasis. Moreover, dexamethasone increases the fluid movements in low grade gliomas and metastases, decreases in high grade gliomas. However, more comprehensive clinical studies are needed to show the effects of dexamethasone on brain tumors and peritumoral edema.

AIm: Bilateral decompression via unilateral approach is one of the minimally invasive methods used for degenerative spinal stenosis. The aim of this retrospective study was to observe the clinical and radiological results of classic laminectomy and bilateral decompression via unilateral approach applied for lumbar stenosis. mATERIAl and mEThods:The data of 40 patients who underwent surgical treatment for lumbar spinal stenosis with different techniques was reviewed retrospectively. The patients were divided into 2 groups according to the surgical technique. In the first group, patients underwent classic laminectomy, while in the second group patients underwent bilateral decompression via unilateral approach. Preoperative and postoperative computed tomography section areas of both groups were examined. Visual analogue scale (VAS) was used to evaluate low back and leg pain in preoperative and postoperative 1, 6, and 12 months. The two groups were compared in respect of surgery time and bleeding. REsulTs:In both groups, postoperative low back and leg pain VAS scores declined compared to the preoperative condition. Low back pain VAS scores were lower at postoperartive 1, 6, and 12 months. The bleeding was higher in the 1st group, whereas the surgery time was higher in the 2nd group.CoNClusIoN: Bilateral decompression through unilateral approach is an effective method without instability effect, which provides sufficient decompression in the degenerative stenosis and increases patient comfort in the postoperative period.KEywoRds: Lumbar stenosis, Unilateral approach, Minimally invasive ÖZ AmAÇ: Dejeneratif lomber dar kanalda kullanılan minimal invaziv yöntemlerden bir tanesi tek taraflı girişimle iki taraflı dekompresyondur. Bu retrospektif çalışmada, klasik laminektomi ile tek taraflı girişimle iki taraflı dekompresyon sağlanan lomber dar kanal hastalarının klinik ve radyolojik sonuçlarını karşılaştırdık. yÖNTEm ve GEREÇlER: Lomber stenoz tanısı olan ve farklı tekniklerle opere edilen 40 hastanın verileri retrospektif olarak değerlendirildi. Hastalar uygulanan cerrahi tekniğe göre 2 ayrı gruba ayrıldı. Birinci gruptaki hastalar klasik laminektomi uygulanan hastalar iken, ikinci gruptaki hastalar ise tek taraflı girişimle iki taraflı dekompresyon yapılan olgulardı. Her iki grup için ameliyat öncesi ve sonrası aksiyel bilgisayarlı tomografi görüntüleri elde edildi. Hastaların bel ve bacak ağrıları 1. ayda, 6. ayda ve 12. ayda vizüel analog skalası (VAS) ile değerlendirildi. Her iki grup ameliyat süresi ve kanama miktarı ile de karşılaştırıldı.BulGulAR: Her iki grupta da ameliyat sonrası bel ve bacak ağrıları için VAS değerlerinde azalma görüldü. İkinci grup için bel ağrısı VAS değerleri 1. ayda, 6. ayda ve 12. ayda birinci gruba göre düşüktü. Kanama miktarı birinci grupta daha fazlayken ameliyat süresi ikinci grupta daha fazlaydı. soNuÇ: Tek taraflı girişimle iki taraflı dekompresyon lomber dar kanal hastalarında kullanılan minimal invaziv, instabilite yaratmadan yeterli dekompresyon sağlayan ve hastanın cerra...

SCIR injury affects lipid peroxidation in rats. Prior splenectomy does not attenuate lipid peroxidation, but prevents neuronal loss after SCIR injury.

Head injuries due to high-velocity missiles and shrapnel as a result of military conflicts have become a very important cause of death or severe neurological deficits. Military-type missiles have high velocities and transfer higher amounts of energy to neural tissue, compared to civil-type missiles. This physical phenomenon also causes greater neural tissue destruction. Shrapnel particles derive from blasts and cause less severe injury because of the irregular particle shape and low energy transmission. This study analyzed 135 patients with head trauma, 80 patients (59%) injured by missiles and 55 patients (41%) by shrapnel. Glasgow Coma Scale (GCS) scores at admission were 3 to 7 in 69 patients, 8 to 10 in 29 patients, and 11 to 15 in 37 patients. The most common anatomical localizations were the right frontoparietal region in 42 patients and the left frontoparietal region in 40 patients. One hundred patients (74%) were operated on immediately and 35 patients (26%) were treated conservatively in the intensive care unit. Ten of the 135 patients died (7.4%), seven from missile injury and three from shrapnel injury. In this study, we found that high mortality was associated with low GCS score at admission, presence of multilobar or skull base injuries, and involvement of ventricles. Early and aggressive surgical intervention decreased the mortality.