Gorlin-Goltz syndrome is a genetically predisposed disease characterised by multiple basal cell carcinomas, odontogenic keratocysts and ectopic calcifications. The aim of this study was to show successful treatment of a 37-year-old male patient by cooperation between different dental and medical specialists. Because of the recurrence of a large basal cell carcinoma after multiple operations and a total dose telecobalt irradiation of 66 Gy, the patient's nose was ablated, with resection of the upper lip and part of the maxilla. The intraoral prosthetic treatment helped to restore the subtotal edentulousness. In order to enhance the application of the dental prosthesis, an Abbe plasty was performed at the second stage of surgery. As previous irradiation of the area precluded the use of facial implants immediately after the intraoral treatment, a temporary artificial nose prosthesis was created. The patient tolerated the procedures well and is completely disease-free 12 months after the surgery. Besides presenting a rare and complicated case of Gorlin-Goltz syndrome, the main purpose of this report is to show that, if different specialists in a dental-clinical team (maxillofacial surgeon, oncologist, radiation oncologist, prosthodontist and psychiatrist) combine their skills and expertise, successful management is possible even in a challenging complex case.
ObjectiveOne‐third of the Hungarian population suffers from xerostomia. Since there is no evidence of the actual prevalence of Sjögren's syndrome (SS) in Hungary, this study aimed to evaluate the same.Materials and MethodsData were collected from the Faculty of Dentistry, Semmelweis University from 2008 to 2015. A diagnosis of SS was established based on the American College of Rheumatology and European League Against Rheumatism criteria.ResultsOf the 1076 patients examined with sicca symptoms, 188 patients had confirmed SS. Primary SS (pSS) was diagnosed in 135 patients and secondary SS (sSS) was confirmed in 53 patients. According to the available statistical records of the public health service of Hungary, there were an average of 16 (0.0014%, 5–26) newly diagnosed SS cases in the entire population and 141 SS patient‐practitioner consultations (49–232) per 100,000 inhabitants in the country over the past 10 years (based on the past 10 years: 2011–2020).ConclusionResults revealed that approximately 1/5th–1/6th of patients with sicca symptoms have SS, among whom 72% and 285 have pSS and sSS, respectively. Global Hungarian records simultaneously revealed that the number of both new diagnoses and doctor‐SS patient encounters has significantly decreased (by 50%) yearly over the last decade.
Objectives of this study were to explore the prevalence of subjective and objective dryness symptoms by smoking status in different age groups, to measure whole and minor saliva flow rates, and to evaluate the possible associations between salivary parameters, oral symptoms and the intensity of smoking in a sample of Hungarian adults. Repeated cross-sectional studies were conducted in 2003 (n=600) and 2014�2018 (n=301) among Hungarian adults visiting regional outpatient dental clinics of their residence where dentist interviewed them about their subjective sicca symptoms and cigarette smoking habits (non-smoker � NS, light smoker � LIS, moderate or heavy smoker � MHS), and measured unstimulated whole saliva flow rate (UWS), palatal- and labial minor saliva flow rates to assess xerostomia objectively. The severity of xerostomia was significantly higher in among 30�39-year-old male smokers (44.8%; p=0.001), and among 18-29-year-old female smokers (52.9%; p=0.013), compared to their non-smoker counterparts (6.7% and 27.1%, respectively). UWS flow rate was significantly lower among 18-29-year-old MHS females compared to NS and LIS females in the same age group (p=0.019, p=0.015, respectively). Significantly increased palatal saliva flow rate was registered among 30�39-year-old MHS males compared to their NS counterparts (p=0.046). Our study highlighted that high intensity of smoking may cause xerostomia, a decrease in the UWS flow rate, and an increase in palatal saliva flow rate in some age groups, however, other sicca symptoms were mostly unrelated to the presence of dry mouth.
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