Introduction: This study analyzed patients with metabolic syndrome and smokers treated with MV140 vaccine to prevent recurrent UTI.
Material and methods: 342 patients with recurrent UTI received MV140 vaccine between 2017 and 2020 in Barcelona, Spain. Variables analyzed: number of UTI at 3 and 6 months after MV140, age, gender, diabetes mellitus, body mass index, hypertension, total cholesterol, HDL-cholesterol, triglycerides and smoking. Patients were divided in Group 1: metabolic syndrome (2 or more variables), Group 2: no metabolic syndrome (less than 2 variables). On the other hand, patients were classified into smokers and non-smokers.
Results: Mean age was 74, 82% were women. At the beginning, 88,9% had 3-5 UTI. Overall effectiveness with MV140 was 72.5% at 3 months and 56.2% at 6 months.
Group 1 (36%) presented 0-1 UTI in 78.9% and 62.6% at 3 and 6 months. In Group 2 (64%) the results were 69% and 52.5%. Comparing both groups, no statistically significant differences were observed (p=0,25, p=0,26). Smokers had 77.4% and 61.3% at 3 and 6 months, and non-smokers had 69.3% and 52.7%. There were also no statistically significant differences (p = 0.5, p = 0.36).
Group 1 and smoking (28,7%) had 82% at 3 months and 66.3% at 6 months. Group 2 and no smoking (71,3%) reached 60.3% and 52% at 3 and 6 months. There were no statistically significant differences between both groups.
Conclusions: The overall efficacy of MV140 was high and safe, without side effects.
Patients with metabolic syndrome and smokers may benefit from this treatment.
BACKGROUNDWe present the case report of a genital fibroepithelial polyp in male at the seventh decade of life, with long evolution of 15 years and benign course. Definitive surgical treatment was surgical excision. We have reviewed the literature and give recommendations on differential diagnosis and treatment.
CASE REPORTA 68-year-old male patient, with a pathological history of hypertension treated with manidipine, hypercholesterolemia treated with atorvastatin and type II diabetes mellitus treated with metformin, went to the emergency department at the hospital due to fever and abdominal pain in the left flank irradiated to the left testis along 12 h before.Physical examination revealed temperature of 38.8°C, abdominal exploration with no findings, and a solid tumor of 20 cm length with a pedicle narrowed to the middle scrotal raphe with erythematous and necrotic areas [Figures 1-3]. Blood tests showed leukocytosis of 14,000 and C-reactive protein of 85. The urine culture was negative. Treatment was started with amoxicillin and amikacin intravenously, and patient presented good improvement.Abdominal ultrasound and computed tomography scan were performed without evidence of pathology. The ultrasound and magnetic resonance imaging of the scrotum revealed testicles within normality and the presence of a non-vascularized para-scrotal mass with a maximum diameter length of 20 cm [Figures 4 and 5].The patient explained that he had the scrotal tumor for 15 years and he had never consulted a doctor before for
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