Epidermodysplasia Verruciformis is a genodermatosis characterized by susceptibility
to infection by specific HPV types (HPV 3/10 and beta-HPVs). It is considered to be
the first model in human carcinogenesis induced by HPV. In this report we present a
rare case of Epidermodysplasia Verruciformis associated with vertical transmission of
HIV. Although most patients with HIV present infections by HPV virus, the frequency
of Epidermodysplasia Verruciformis is no greater in patients with HIV because in EV
there is a deficiency of specific cellular immunity to infection by some types of
HPV, called HPV-related Epidermodysplasia Verruciformis.
Hansen's disease is a chronic infecto-contagious disease caused by Mycobacterium
leprae. The bacillus prefers low-temperature areas and the nose is usually the
initial site of lesions. Transmission of the bacilli occurs by nasal and
oropharyngeal secretions, and through solutions of continuity of the skin and/or
mucosae. Nasal manifestations are found in the later stages of the disease.
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